{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T12:42:06Z","timestamp":1769085726086,"version":"3.49.0"},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"2","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1991,8,1]]},"abstract":"<jats:p>1. Exercise-induced haemolysis has been implicated in the sub-optimal iron status of endurance-trained athletes. Accordingly, erythrocyte survival studies using 51Cr were performed on male and female distance runners (n = 20) and sedentary control subjects (n = 10) in order to determine whether the rate of erythrocyte destruction was altered as a consequence of repetitive exercise training.<\/jats:p>\n               <jats:p>2. The chromium half-disappearance time of the male (25.4 \u00b1 3.6 days, mean \u00b1 sd) but not the female (28.3 \u00b1 4.6 days) athletes was significantly lower than that of the male (33.1 \u00b1 4.5 days) and female (32.3 \u00b1 2.6 days) control subjects (P &amp;lt; 0.01). The mean erythrocyte lifespan of the male and female distance runners (67.2 \u00b1 22.2 and 72.4 \u00b1 26.0 days, respectively) was significantly shorter than that of the non-exercising male and female subjects (113.4 \u00b1 31.0 and 114.1 \u00b1 29.0 days, respectively) (P &amp;lt; 0.01).<\/jats:p>\n               <jats:p>3. There was no correlation between the mean erythrocyte lifespan and the haemoglobin concentration, serum ferritin levels, body mass, weekly training distance, number of years running or daily protein intake. The mean cell volume and reticulocyte count measured in the same athletes before and after completing a standard 42 km marathon race were within the normal range, whereas the plasma haemoglobin levels were elevated (77.0 \u00b1 50.5 mg\/l) and the serum haptoglobin levels were decreased (0.89 \u00b1 0.4 g\/l) at rest, with a further significant decrease after running (0.69 \u00b1 0.4 g\/l) in the latter measurement (P &amp;lt; 0.05).<\/jats:p>\n               <jats:p>4. It is concluded that the demonstrated increase in erythrocyte turnover may be sufficient to precipitate an iron deficiency in endurance athletes when dietary intake or absorption does not meet the accelerated erythropoietic demands.<\/jats:p>","DOI":"10.1042\/cs0810147","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T11:33:17Z","timestamp":1438947197000},"page":"147-152","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":80,"title":["Haemolytic effects of exercise"],"prefix":"10.1042","volume":"81","author":[{"given":"Lindsay M.","family":"Weight","sequence":"first","affiliation":[{"name":"University of Cape Town Leukaemia Centre, University of Cape Town Medical School, Cape Town, South Africa"},{"name":"Department of Haematology, University of Cape Town Medical School, Cape Town, South Africa"}]},{"given":"Michael J.","family":"Byrne","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Groote Schuur Hospital, Cape Town, South Africa"}]},{"given":"Peter","family":"Jacobs","sequence":"additional","affiliation":[{"name":"University of Cape Town Leukaemia Centre, University of Cape Town Medical School, Cape Town, South Africa"},{"name":"Department of Haematology, University of Cape Town Medical School, Cape Town, South Africa"}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/81\/2\/147\/463054\/cs0810147.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/portlandpress.com\/clinsci\/article-pdf\/81\/2\/147\/463054\/cs0810147.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T22:36:10Z","timestamp":1638398170000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/81\/2\/147\/75349\/Haemolytic-effects-of-exercise"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,8,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1991,8,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0810147","relation":{},"ISSN":["0143-5221","1470-8736"],"issn-type":[{"value":"0143-5221","type":"print"},{"value":"1470-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,8,1]]}}}