{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T21:19:24Z","timestamp":1777670364847,"version":"3.51.4"},"reference-count":0,"publisher":"Portland Press Ltd.","issue":"2","content-domain":{"domain":["portlandpress.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1998,8,1]]},"abstract":"<jats:p>1.Many human fetuses have to adapt to a limited supply of nutrients. In doing so they permanently change their structure and metabolism.<\/jats:p>\n               <jats:p>2.These \u2018programmed' changes may be the origins of a number of diseases in later life, including coronary heart disease and the related disorders stroke, diabetes and hypertension.<\/jats:p>\n               <jats:p>3.This review examines the evidence linking these diseases to fetal undernutrition and provides an overview of previous studies in this area.<\/jats:p>","DOI":"10.1042\/cs0950115","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T11:40:53Z","timestamp":1438947653000},"page":"115-128","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":1353,"title":["In utero programming of chronic disease"],"prefix":"10.1042","volume":"95","author":[{"given":"D. J. P.","family":"BARKER","sequence":"first","affiliation":[{"name":"MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD, U.K."}]}],"member":"288","container-title":["Clinical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/95\/2\/115\/466981\/cs0950115.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/portlandpress.com\/clinsci\/article-pdf\/95\/2\/115\/466981\/cs0950115.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T00:16:50Z","timestamp":1684109810000},"score":1,"resource":{"primary":{"URL":"https:\/\/portlandpress.com\/clinsci\/article\/95\/2\/115\/76990\/In-utero-programming-of-chronic-disease"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,8,1]]},"references-count":0,"aliases":["10.1042\/cs19980019"],"journal-issue":{"issue":"2","published-print":{"date-parts":[[1998,8,1]]}},"URL":"https:\/\/doi.org\/10.1042\/cs0950115","relation":{},"ISSN":["0143-5221","1470-8736"],"issn-type":[{"value":"0143-5221","type":"print"},{"value":"1470-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,8,1]]}}}