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In the present paper, we review the evidence supporting the proposed mechanisms of Rab targeting and highlight insights into this process provided by studies of Rab27a.<\/jats:p>","DOI":"10.1042\/bst20120200","type":"journal-article","created":{"date-parts":[[2012,11,23]],"date-time":"2012-11-23T17:09:55Z","timestamp":1353690595000},"page":"1383-1388","update-policy":"https:\/\/doi.org\/10.1042\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Rab27a and melanosomes: a model to investigate the membrane targeting of Rabs"],"prefix":"10.1042","volume":"40","author":[{"given":"Antonia\u00a0E.G.","family":"Booth","sequence":"first","affiliation":[{"name":"Molecular Medicine, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, U.K."}]},{"given":"Miguel\u00a0C.","family":"Seabra","sequence":"additional","affiliation":[{"name":"Molecular Medicine, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, U.K."},{"name":"CEDOC, Faculdade de Ciencias Medicas, Universidade Nova de Lisboa, Lisbon, Portugal"}]},{"given":"Alistair\u00a0N.","family":"Hume","sequence":"additional","affiliation":[{"name":"School of Biomedical Science, University of Nottingham, Nottingham NG7 2UH, U.K."}]}],"member":"288","published-online":{"date-parts":[[2012,11,21]]},"reference":[{"key":"2021111720443583100_B1","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/nrm2728","article-title":"RabGTPases as coordinators of vesicle traffic","volume":"10","author":"Stenmark","year":"2009","journal-title":"Nat. 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