{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T04:37:00Z","timestamp":1792471020333,"version":"4.5.0"},"reference-count":17,"publisher":"American Speech Language Hearing Association","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Speech Lang Pathol"],"published-print":{"date-parts":[[2019,2,21]]},"abstract":"\n Purpose<\/jats:title>\n Pharyngeal high-resolution manometry is an emerging practice for diagnosis of swallowing disorders in the upper aerodigestive tract. Advancement of a catheter through the upper esophageal sphincter may introduce safety considerations. There are no published studies of catheter placement complications, side effects, or tolerability. This study examines patient-reported side effects and tolerability of pharyngeal high-resolution manometry.<\/jats:p>\n <\/jats:sec>\n \n Method<\/jats:title>\n Data were collected prospectively from 133 adult patients who underwent pharyngeal high-resolution manometry for the 1st time. Patients rated tolerability specific to \u201cnose\u201d and \u201cthroat\u201d using a visual analog scale for 4 procedure time points: catheter passage, during the procedure, catheter removal, and after the procedure. Complications during catheter passage and removal were recorded. A telephone call was placed to the patient within 6 days to survey side effects experienced after the procedure.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The patient sample was composed of 91 males and 42 females with a mean age of 66 years (\n SD<\/jats:italic>\n = 14.4). Tolerability scores for catheter passage showed no significant difference (\n p<\/jats:italic>\n = .7288) in the nose versus throat. Tolerability for females was significantly less (\n p<\/jats:italic>\n = .0144) than that for males. Participants with the shortest procedure duration showed greatest discomfort in the nose (\n p<\/jats:italic>\n = .0592) and throat (\n p<\/jats:italic>\n = .0286). Complications included gag response (14%), emesis (2%), and epistaxis (< 1%). Side effects included sore throat (16%), nose discomfort (16%), coughing (11 %), nosebleed (4%), and nausea\/vomiting (4%).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n High-resolution manometry appears to have high patient tolerability with low incidence of side effects. Rates of complications and side effects are similar to those reported for other transnasal procedures.<\/jats:p>\n <\/jats:sec>","DOI":"10.1044\/2018_ajslp-18-0039","type":"journal-article","created":{"date-parts":[[2018,12,5]],"date-time":"2018-12-05T02:00:49Z","timestamp":1543975249000},"page":"43-52","source":"Crossref","is-referenced-by-count":21,"title":["Safety and Tolerability of Pharyngeal High-Resolution Manometry"],"prefix":"10.1044","volume":"28","author":[{"given":"Molly A.","family":"Knigge","sequence":"first","affiliation":[{"name":"University of Wisconsin\u2013Madison"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stevie","family":"Marvin","sequence":"additional","affiliation":[{"name":"University of Wisconsin\u2013Madison"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan L.","family":"Thibeault","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Wisconsin\u2013Madison"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1310","reference":[{"key":"e_1_3_2_2_1","unstructured":"American Speech-Language-Hearing Association. 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