{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T12:36:11Z","timestamp":1765888571923},"reference-count":44,"publisher":"American Speech Language Hearing Association","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Audiol"],"published-print":{"date-parts":[[2021,6,14]]},"abstract":"<jats:sec>\n            <jats:title>Purpose<\/jats:title>\n            <jats:p>The brainstem dysfunction in multiple sclerosis (MS) often causes significant functional impairment leading to disability. This study aims to explore modified brainstem auditory evoked potential (BAEP) scores based on the pattern of BAEP abnormalities and relate with brainstem symptoms, brainstem functional system scores (BFSS), brainstem lesions, and disability.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Method<\/jats:title>\n            <jats:p>Forty-five participants with relapsing\u2013remitting MS and 45 age- and gender-matched healthy controls underwent case history assessment, otoscopic examination, pure-tone audiometry, and BAEP testing. Also, neurological examination (Expanded Disability Status Scale, FSS scales) and magnetic resonance imaging were carried out on MS participants. Patterns of BAEP abnormalities were categorized and converted to BAEP scores.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>\n              Out of 45 participants' brainstem symptoms, BFSS &gt; 1, brainstem lesions (magnetic resonance imaging), and BAEP abnormalities were observed in 75.6%, 42.2%, 62.2%, and 55.56% of participants, respectively. Waves V and III abnormalities were more common among MS participants and showed a significant difference from the control group in the Mann\u2013Whitney\n              <jats:italic>U<\/jats:italic>\n              test. Chi-square test did not show a significant association of BAEP abnormalities with brainstem symptoms and lesions but showed significant association with BFSS. The mean and standard deviation of BAEP scores in MS participants were 1.73 + 2.37. All healthy controls showed BAEP scores of 0. BAEP scores in MS participants showed significant correlation with BFSS scores and predict Expanded Disability Status Scale scores.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>BAEP scores based on the pattern of BAEP abnormality can be a valid and useful measure in evaluating brainstem functions and predicting disability in MS.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1044\/2020_aja-20-00155","type":"journal-article","created":{"date-parts":[[2021,3,26]],"date-time":"2021-03-26T20:08:20Z","timestamp":1616789300000},"page":"255-265","source":"Crossref","is-referenced-by-count":7,"title":["Effectiveness of Brainstem Auditory Evoked Potentials Scoring in Evaluating Brainstem Dysfunction and Disability Among Individuals With Multiple Sclerosis"],"prefix":"10.1044","volume":"30","author":[{"given":"Vignesh Sangu","family":"Srinivasan","sequence":"first","affiliation":[{"name":"Department of Neurology, Tamil Nadu Government Multi Super Speciality Hospital, Chennai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajalakshmi","family":"Krishna","sequence":"additional","affiliation":[{"name":"Department of Audiology, All India Institute of Speech and Hearing, Mysuru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhoopathy Rangappan","family":"Munirathinam","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tamil Nadu Government Multi Super Speciality Hospital, Chennai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1310","reference":[{"issue":"3","key":"e_1_3_1_2_1","first-page":"235","article-title":"BSER abnormalities in a multiple sclerosis patient with normal peripheral hearing acuity","volume":"4","author":"Arnold J. 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