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Children's residual hearing was measured by pure-tone audiometry at different frequencies. Multiple linear regression models were conducted to examine the effects of residual hearing and the use of HAs on GM volume in the auditory cortex with the control of age and gender.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Children with more residual hearing at high frequencies had larger GM volume ratio (corrected by total intracranial volume) in the left Heschl's gyrus (<jats:italic>r<\/jats:italic>= \u2212.545,<jats:italic>p<\/jats:italic>= .013). An interaction effect between residual hearing and the use of HAs suggested that the effect of residual hearing on GM ratio was moderated by the use of HAs (\u03b2 = \u2212.791,<jats:italic>p<\/jats:italic>= .020). Compared with children with less residual hearing, children who had more residual hearing benefited more from longer use of HAs in terms of a larger GM ratio.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Our preliminary findings highlight the impact of residual hearing on the neuroanatomy of the auditory cortex in children with hearing loss. Moreover, our results call for more auditory input via HAs for children with more residual hearing to preserve the auditory cortex before cochlear implantation. For children with less residual hearing who might receive limited benefit from HAs, an early cochlear implant would be necessary.<\/jats:p><\/jats:sec>","DOI":"10.1044\/2023_aja-22-00172","type":"journal-article","created":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T22:55:50Z","timestamp":1682031350000},"page":"379-390","source":"Crossref","is-referenced-by-count":4,"title":["The Extent of Hearing Input Affects the Plasticity of the Auditory Cortex in Children With Hearing Loss: A Preliminary Study"],"prefix":"10.1044","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3570-2729","authenticated-orcid":false,"given":"Di","family":"Yuan","sequence":"first","affiliation":[{"name":"Department of Psychology, The Chinese University of Hong Kong, Hong Kong SAR"},{"name":"Brain and Mind Institute, The Chinese University of Hong Kong, Hong Kong SAR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris H.-Y.","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, The Chinese University of Hong Kong, Hong Kong SAR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gangyi","family":"Feng","sequence":"additional","affiliation":[{"name":"Brain and Mind Institute, The Chinese University of Hong Kong, Hong Kong SAR"},{"name":"Department of Linguistics and Modern Languages, The Chinese University of Hong Kong, Hong Kong SAR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wai Tsz","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, The Chinese University of Hong Kong, Hong Kong SAR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C. 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