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This review will cover our current understanding of the impact of, and mechanisms underlying, aminoglycoside-induced vestibulotoxicity and highlight the gaps in our knowledge that remain.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>Aminoglycoside-induced vestibular deficits have long-term impacts on patients across the lifespan. Additionally, the prevalence of aminoglycoside-induced vestibulotoxicity appears to be greater than cochleotoxicity. Thus, monitoring for vestibulotoxicity should be independent of auditory monitoring and encompass patients of all ages from young children to older adults before, during, and after aminoglycoside therapy.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1044\/2023_aja-22-00199","type":"journal-article","created":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T20:03:44Z","timestamp":1686859424000},"page":"746-760","source":"Crossref","is-referenced-by-count":4,"title":["Mechanisms and Impact of Aminoglycoside-Induced Vestibular Deficits"],"prefix":"10.1044","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5955-7506","authenticated-orcid":false,"given":"Kristen","family":"Janky","sequence":"first","affiliation":[{"name":"Department of Audiology, Boys Town National Research Hospital, Omaha, NE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6103-5237","authenticated-orcid":false,"given":"Peter S.","family":"Steyger","sequence":"additional","affiliation":[{"name":"Bellucci Translational Hearing Center, Creighton University, Omaha, NE"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1310","reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-012-6724-y"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja11.10850"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31822a2107"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022347"},{"issue":"5","key":"e_1_3_2_6_1","first-page":"632","article-title":"A dual-task study of interference between mental activity and control of balance","volume":"19","author":"Andersson G.","year":"1998","unstructured":"Andersson, G., Yardley, L., & Luxon, L. 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