{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T12:27:12Z","timestamp":1777033632104,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2002,3,19]],"date-time":"2002-03-19T00:00:00Z","timestamp":1016496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Microbiology and Immunology"],"published-print":{"date-parts":[[2002,4]]},"abstract":"<jats:p>This prospective study was designed to investigate amoxicillin\u2010resistant oral anaerobes, and to identify their \u03b2\u2010lactamase\u2010encoding genes. Three subgingival bacterial samples were collected from 12 patients suffering from periodontitis. One to seven \u03b2\u2010lactamase\u2010producing strains were obtained from each patient, mostly belonging to the <jats:italic>Prevotella<\/jats:italic> genus (<jats:italic>Bacteroides eggerthii<\/jats:italic>, 2\/35 strains; <jats:italic>Prevotella<\/jats:italic> sp., 33\/35 strains). PCR assays were used to detect <jats:italic>cfxA<\/jats:italic> and <jats:italic>cepA\/cblA<\/jats:italic>, the genes encoding class A\/group2e \u03b2\u2010lactamases previously described in the <jats:italic>Bacteroides fragilis<\/jats:italic> group. The present investigation confirmed the role of <jats:italic>Prevotella<\/jats:italic> species as \u03b2\u2010lactamase producers in periodontal pockets. Additionally, this PCR screening showed (1): the high prevalence of CfxA \u03b2\u2010lactamase production by aminopenicillin\u2010resistant <jats:italic>Prevotella<\/jats:italic> (32\/33: 97.0% positive strains) vs. <jats:italic>cepA\/cblA<\/jats:italic> (1\/33: 3.0% positive strains), and (2) the presence of <jats:italic>cfxA<\/jats:italic> in the periodontal reservoir in the absence of antimicrobial therapy during the previous 6\u2003months.<\/jats:p>","DOI":"10.1046\/j.0902-0055.2001.00096.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T15:51:47Z","timestamp":1047484307000},"page":"85-88","source":"Crossref","is-referenced-by-count":43,"title":["High prevalence of <i>cfxA<\/i>\u03b2\u2010lactamase in aminopenicillin\u2010resistant <i>Prevotella<\/i> strains isolated from periodontal pockets"],"prefix":"10.1111","volume":"17","author":[{"given":"T.","family":"Fosse","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Madinier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Hannoun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Giraud\u2010Morin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Hitzig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Charbit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Ourang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,3,19]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1998.tb00748.x"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-302X.1999.140604.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-146-5-1241"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.39.7.1458"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.41.187"},{"key":"e_1_2_5_7_2","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1128\/AAC.43.5.1270","article-title":"\u03b2\u2010lactamase production and antimicrobial susceptibility of oral heterogeneous Fusobacterium nucleatum populations in young children","volume":"43","author":"K\u00f6n\u00f6nen E","year":"1999","journal-title":"Antimicrob Agents Chemother"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-302x.2001.160102.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1996.tb00182.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.8.2386-2389.2001"},{"key":"e_1_2_5_11_2","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1128\/AAC.40.4.1014","article-title":"Oligonucleotide probes for detection of cephalosporinases among Bacteroides strains","volume":"40","author":"Mastrantonio P","year":"1996","journal-title":"Antimicrob Agents Chemother"},{"key":"e_1_2_5_12_2","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1128\/AAC.43.10.2383","article-title":"\u03b2\u2010lactamase production in Prevotella intermedia, Prevotella nigrescens, and Prevotella pallens genotypes and in vitro susceptibilities to selected antimicrobial agents","volume":"43","author":"M\u00e4tt\u00f6 J","year":"1999","journal-title":"Antimicrob Agents Chemother"},{"key":"e_1_2_5_13_2","volume-title":"Approved Standard. 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