{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T06:44:16Z","timestamp":1701845056987},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,1,6]],"date-time":"2004-01-06T00:00:00Z","timestamp":1073347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2004,2]]},"abstract":"<jats:title>Abstract:<\/jats:title><jats:p>The prognosis of nasal natural killer (NK)\/T\u2010cell lymphoma with cutaneous involvement especially is morbid despite intensive chemotherapy and radiotherapy. We treated a 52\u2010yr\u2010old Japanese woman with cutaneous dissemination of nasal NK\/T\u2010cell lymphoma. Six cycles of chemotherapy, irradiation to skin lesion were administered and complete remission (CR) was attained. High\u2010dose chemotherapy (HDC; etoposide 750\u2003mg\/m<jats:sup>2<\/jats:sup>\u2003\u00d7\u20032\u2003d, cyclophosphamide 60\u2003mg\/kg\u2003\u00d7\u20032\u2003d, total body irradiation 12\u2003Gy two daily fractions\u2003\u00d7\u20033\u2003d) followed by CD34<jats:sup>+<\/jats:sup>\u2010selected autologous peripheral blood stem cell transplantation (CD34<jats:sup>+<\/jats:sup>\u2010APBSCT) was then prescribed. Complete remission (CR) was obtained and she has been free of disease for 34\u2003months since CD34<jats:sup>+<\/jats:sup>\u2010APBSCT. We suggest that marrow\u2010ablative chemotherapy facilitated by autologous stem cell transplantation should be considered part of the primary therapy for subjects with a poor prognosis for nasal NK\/T\u2010cell lymphoma with cutaneous involvement.<\/jats:p>","DOI":"10.1046\/j.0902-4441.2003.00170.x","type":"journal-article","created":{"date-parts":[[2004,1,6]],"date-time":"2004-01-06T14:08:40Z","timestamp":1073398120000},"page":"140-144","source":"Crossref","is-referenced-by-count":9,"title":["Effective high\u2010dose chemotherapy combined with CD34<sup>+<\/sup>\u2010selected peripheral blood stem cell transplantation in a patient with cutaneous involvement of nasal NK\/T\u2010cell 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