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Blood vessels were identified with monoclonal antibody for von Willebrand's factor.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold>A significantly larger number of vessels were observed in inflamed tissues of non\u2010smokers than smokers (<jats:italic>P<\/jats:italic>&lt;0.05). The number and proportion of vessels expressing both ICAM\u20101 and E\u2010selectin was greater in sites with inflammation compared to non\u2010inflamed sites in both smokers and non\u2010smokers (<jats:italic>P<\/jats:italic>&lt;0.05). The proportion of the total number of vessels expressing ICAM\u20101 in non\u2010inflamed sites was greater in non\u2010smokers compared with smokers (<jats:italic>P<\/jats:italic>&lt;0.05).<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold>These results suggest that the inflammatory response in smokers with periodontitis may not be accompanied by an equivalent increase in vascularity. Reduced ICAM\u20101 expression in non\u2010inflamed areas of smokers could reflect a systemic effect of tobacco smoking on ICAM\u20101 independent of inflammation.<\/jats:p>","DOI":"10.1046\/j.0904-2512.2001.joptest.doc.x","type":"journal-article","created":{"date-parts":[[2010,10,29]],"date-time":"2010-10-29T19:09:52Z","timestamp":1288379392000},"page":"59-64","source":"Crossref","is-referenced-by-count":63,"title":["Expression of ICAM\u20101 and E\u2010selectin in gingival tissues of smokers and non\u2010smokers with periodontitis"],"prefix":"10.1111","volume":"31","author":[{"given":"K.","family":"Rezavandi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. M.","family":"Palmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. W.E. W.","family":"Odell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. 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