{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T13:52:52Z","timestamp":1711547572166},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,9,23]],"date-time":"2008-09-23T00:00:00Z","timestamp":1222128000000},"content-version":"vor","delay-in-days":2398,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropathology"],"published-print":{"date-parts":[[2002,3]]},"abstract":"<jats:p>The present report concerns the demonstration and distribution of tau\u2010positive structures in the frontal and temporal white matter of five autopsy cases of early onset Alzheimer\u2019s disease (AD). The relationship between white matter lesions and tau positive structures was also investigated. Five early onset AD brains, which had not only unambiguous white matter lesions, but also no or rare atherosclerosis and minimal amyloid angiopathy, were examined. There were several tau\u2010positive coiled body\u2010like structures and many thread\u2010like structures in the white matter, although previous reports showed only a few coiled bodies in the white matter in the AD brain. No relationship was found between the degree of each white matter lesion and number or distribution of tau\u2010positive structures in the white matter. The results suggest that the AD brain has tau\u2010positive structures in the white matter similar to some neurodegenarative brain diseases such as progressive supranuclear palsy, corticobasal degeneration, and dementia with grains. However, tau abnormalities may have fewer effects when they are located in white matter lesions in AD.<\/jats:p>","DOI":"10.1046\/j.0919-6544.2002.00422.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T15:08:11Z","timestamp":1047481691000},"page":"9-12","source":"Crossref","is-referenced-by-count":10,"title":["Demonstration and distribution of tau\u2010positive glial coiled body\u2010like structures in white matter and white matter threads in early onset Alzheimer\u2019s disease"],"prefix":"10.1111","volume":"22","author":[{"given":"Takahiko","family":"Umahara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuniaki","family":"Tsuchiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenzi","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoshi","family":"Kanaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiko","family":"Iwamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masharu","family":"Takasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoshi","family":"Mukai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriyuki","family":"Shibata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinsuke","family":"Kato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,9,23]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.1989.tb01146.x"},{"key":"e_1_2_5_3_2","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s004010100365","article-title":"Argyrophilic grain dementia mimicking temporal Pick\u2019s disease: A clinical, radiological, and pathological study of an autopsy case with a clinical course of 15 years","volume":"102","author":"Tsuchiya K","year":"2001","journal-title":"Acta Neuropathol (Berl)"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(90)90028-8"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1789.1999.00252.x"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00293314"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004010050728"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(94)90010-8"},{"key":"e_1_2_5_9_2","first-page":"1052","article-title":"Immunocytochemical characterization of glial fibrillary tangles in Alzheimer\u2019s disease brain","volume":"146","author":"Nishimura M","year":"1995","journal-title":"Am J Pathol"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1789.1996.tb00158.x"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004010000213"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00227819"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1992.tb05204.x"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00308809"}],"container-title":["Neuropathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.0919-6544.2002.00422.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1046\/j.0919-6544.2002.00422.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T19:31:30Z","timestamp":1697571090000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1046\/j.0919-6544.2002.00422.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,3]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2002,3]]}},"alternative-id":["10.1046\/j.0919-6544.2002.00422.x"],"URL":"https:\/\/doi.org\/10.1046\/j.0919-6544.2002.00422.x","archive":["Portico"],"relation":{},"ISSN":["0919-6544","1440-1789"],"issn-type":[{"value":"0919-6544","type":"print"},{"value":"1440-1789","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,3]]}}}