{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T09:29:48Z","timestamp":1789810188447,"version":"4.0.1"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2008,7,7]],"date-time":"2008-07-07T00:00:00Z","timestamp":1215388800000},"content-version":"vor","delay-in-days":2685,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brit J Clinical Pharma"],"published-print":{"date-parts":[[2001,3]]},"abstract":"<jats:p><jats:bold>Aims\u2002<\/jats:bold> To determine whether DTPP+Hib vaccination (diphtheria, tetanus, pertussis, poliomyelitis +\/\u2212 haemophilus) increased the risk of sudden unexpected death (SUD) in children under 3\u2003months of age.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> We conducted a multicentre case\u2010control study in the 28 French \u2018SIDS Centers\u2019. Case selection was based on death labelled sudden infant death syndrome (SIDS) of an infant aged between 30 and 90\u2003days. Three living controls were selected, matched for sex, gestational age and born immediately after the victim in the same maternity unit.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> We identified 114 cases of SUD aged between 30 and 90\u2003days and 341 live controls matched for age and sex and born in the same maternity unit as the case. DTPP\u00b1Hib immunization did not increase the risk of SUD (OR 1.08) (95% CI 0.49, 2.36) in children under 3\u2003months of age when adjusted for sleeping position, illness in the week before death, maternal tobacco consumption, birth weight, type of mattress, breastfeeding and sex. However, low birth\u2010weight (6.53 [2.29, 18.9]), multiple birth (5.1 [1.76, 15.13]), no breastfeeding (1.77 [1.1, 2.85]), prone sleeping position (9.8 [5, 8, 18, 9]), soft mattress (3.26 [1.69, 6.29]), recent illness (3.44 [1.84, 6.41]) and parental smoking (1.74 [1.2, 2.96]) were confirmed as risk factors in early SIDS.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> DTPP\u00b1Hib immunization is not a risk factor for early SUD. In this population, we found the same risk factors as described for SIDS.<\/jats:p>","DOI":"10.1046\/j.1365-2125.2001.00341.x","type":"journal-article","created":{"date-parts":[[2003,3,10]],"date-time":"2003-03-10T23:40:59Z","timestamp":1047339659000},"page":"271-276","source":"Crossref","is-referenced-by-count":43,"title":["Sudden unexpected death in infants under 3\u2003months of age and vaccination status \u2013 a case\u2010control 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