{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T23:03:58Z","timestamp":1785711838848,"version":"3.56.0"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":6209,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["British Journal of Dermatology"],"published-print":{"date-parts":[[1998,9]]},"DOI":"10.1046\/j.1365-2133.1998.02409.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T05:10:42Z","timestamp":1047359442000},"page":"453-461","source":"Crossref","is-referenced-by-count":26,"title":["Epidermal Langerhans cell apoptosis is induced<i>in vivo<\/i>by nonanoic acid but not by sodium lauryl sulphate"],"prefix":"10.1093","volume":"139","author":[{"family":"Forsey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Shahidullah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Sands","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Mcvittie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Aldridge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Hunter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Howie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2008,10,9]]},"reference":[{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB1|cit1","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1111\/j.1600-0536.1993.tb03347.x","article-title":"An arm immersion model of compromised skin. (I) Influence on irritation reactions","volume":"28","author":"Allenby","year":"1993","journal-title":"Contact Dermatitis"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB2|cit2","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/S0190-9622(94)70114-8","article-title":"Surfactant induced skin irritation and repair","volume":"30","author":"Wilhelm","year":"1994","journal-title":"J Am Acad Dermatol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB3|cit3","unstructured":"Bruze M Emmett E Irritant Contact Dermatitis 1990 81 106"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB4|cit4","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/j.1600-0536.1994.tb02019.x","article-title":"The modulation of skin irritation","volume":"31","author":"Berardesca","year":"1994","journal-title":"Contact Dermatitis"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB5|cit5","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0167-5699(93)90062-P","article-title":"The skin immune system: progress in cutaneous biology","volume":"14","author":"Bos","year":"1993","journal-title":"Immunol Today"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB6|cit6","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/1523-1747.ep12319895","article-title":"Epidermal damage induced by irritants in man: a light and electron microscopic study","volume":"93","author":"Willis","year":"1989","journal-title":"J Invest Dermatol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB7|cit7","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/1523-1747.ep12365561","article-title":"Differential patterns of epidermal leukocyte infiltration in patch test reactions to structurally unrelated chemical irritants","volume":"101","author":"Willis","year":"1993","journal-title":"J Invest Dermatol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB8|cit8","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/BF00371567","article-title":"Distributional changes of Langerhans cells in human skin during irritant contact dermatitis","volume":"286","author":"Mikulowska","year":"1994","journal-title":"Arch Dermatol Res"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB9|cit9","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1111\/j.1600-0536.1984.tb00961.x","article-title":"Lymphocytes and Langerhans cells in patch tests","volume":"11","author":"Kanerva","year":"1984","journal-title":"Contact Dermatitis"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB10|cit10","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/1523-1747.ep12514510","article-title":"Differential effects of structurally unrelated chemical irritants on the density and morphology of epidermal CD1+ cells","volume":"95","author":"Willis","year":"1990","journal-title":"J Invest Dermatol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB11|cit11","doi-asserted-by":"crossref","first-page":"384","DOI":"10.2340\/0001555571384388","article-title":"Differential effects of sodium lauryl sulfate and nonanoic acid on the expression of CD1a and ICAM-1 in human epidermis","volume":"71","author":"Lindberg","year":"1990","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB12|cit12","first-page":"81","article-title":"Phenotypic characterisation in situ of inflammatory cells in allergic and irritant contact dermatitis in man","volume":"55","author":"Scheynius","year":"1984","journal-title":"Clin Exp Immunol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB13|cit13","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1111\/1523-1747.ep12395694","article-title":"Increases in human epidermal DR+CD1+, DR+CD1-CD36+ and DR-CD3+ cells in allergic versus irritant patch test responses","volume":"103","author":"Gerberick","year":"1994","journal-title":"J Invest Dermatol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB14|cit14","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1111\/j.1600-0536.1987.tb01445.x","article-title":"Sequential immunophenotypic study of lymphoid infiltrate in allergic and irritant reactions","volume":"16","author":"Avnstorp","year":"1987","journal-title":"Contact Dermatitis"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB15|cit15","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1111\/1523-1747.ep12696867","article-title":"Decreased numbers of antigen presenting cells in the skin following application of irritant agents: relevance for skin cancer","volume":"92","author":"Lisby","year":"1989","journal-title":"J Invest Dermatol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB16|cit16","doi-asserted-by":"crossref","first-page":"117","DOI":"10.2340\/0001555566117120","article-title":"Dynamic changes in the epidermal OKT6 positive cells at mild irritant reactions in human skin","volume":"66","author":"Lindberg","year":"1986","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB17|cit17","doi-asserted-by":"crossref","first-page":"348","DOI":"10.2340\/0001555572348351","article-title":"Quantitative analysis of Langerhans cells in epidermis at irritant contact reactions using confocal laser scanning microscopy","volume":"72","author":"Scheynius","year":"1992","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB18|cit18","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/j.1365-2133.1993.tb15149.x","article-title":"Large increase of Langerhans cells in human skin lymph derived from irritant contact dermatitis","volume":"128","author":"Brand","year":"1993","journal-title":"Br J Dermatol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB19|cit19","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.1365-2133.1994.tb08530.x","article-title":"The UK Working Party's Diagnostic Criteria for Atopic Dermatitis. I. Derivation of a minimum set of discriminators for atopic dermatitis","volume":"131","author":"Williams","year":"1994","journal-title":"Br J Dermatol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB20|cit20","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/bjc.1972.33","article-title":"Apoptosis: a basic biological phenomenon with wide ranging implications in tissue kinetics","volume":"26","author":"Kerr","year":"1972","journal-title":"Br J Cancer"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB21|cit21","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/BF00048057","article-title":"Apoptosis and the regulation of cell numbers","volume":"11","author":"Wyllie","year":"1992","journal-title":"Cancer Metast Rev"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB22|cit22","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1365-2249.1994.tb06036.x","article-title":"Peripheral T lymphocyte depletion by apoptosis after CD4 ligation in vivo: selective loss of CD44-ve and \u2018activating\u2019 memory T cells","volume":"95","author":"Howie","year":"1994","journal-title":"Clin Exp Immunol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB23|cit23","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S0190-9622(82)80229-6","article-title":"A new look at conditioned hyperirritability","volume":"7","author":"Roper","year":"1982","journal-title":"J Am Acad Dermatol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB24|cit24","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1111\/j.1600-0536.1985.tb02554.x","article-title":"Skin irritancy from nonanoic acid","volume":"13","author":"Wahlberg","year":"1985","journal-title":"Contact Dermatitis"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB25|cit25","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/1523-1747.ep12616147","article-title":"Differential effects of structurally unrelated chemical irritants on the density of proliferating keratinocytes in 48\u2003h patch test","volume":"99","author":"Willis","year":"1992","journal-title":"J Invest Dermatol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB26|cit26","doi-asserted-by":"crossref","first-page":"S109","DOI":"10.1111\/1523-1747.ep12669997","article-title":"Studies on human skin lymph containing Langerhans cells from sodium lauryl sulfate contact dermatitis","volume":"99","author":"Brand","year":"1992","journal-title":"J Invest Dermatol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB27|cit27","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1365-2133.1995.tb08622.x","article-title":"Activated immunocompetent cells in human skin lymph derived from irritant contact dermatitis: an immunomorphological study","volume":"132","author":"Brand","year":"1995","journal-title":"Br J Dermatol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB28|cit28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-0536.1995.tb00438.x","article-title":"The sodium lauryl sulfate model: an overview","volume":"33","author":"Lee","year":"1995","journal-title":"Contact Dermatitis"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB29|cit29","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1600-0536.1996.tb02143.x","article-title":"Allergic and irritant patch test reactions and atopic disease","volume":"34","author":"Klas","year":"1996","journal-title":"Contact Dermatitis"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB30|cit30","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1001\/archderm.1994.01690110068008","article-title":"Abnormal skin irritancy in atopic dermatitis and in atopy without dermatitis","volume":"130","author":"Nassif","year":"1994","journal-title":"Arch Dermatol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB31|cit31","first-page":"3","article-title":"New views on epidermis and its Langerhans cells in the normal state and in contact dermatitis","volume":"99","author":"Falck","year":"1981","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB32|cit32","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1146\/annurev.iy.09.040191.001415","article-title":"The dendritic cell system and its role in immunogenicity","volume":"9","author":"Steinman","year":"1991","journal-title":"Annu Rev Immunol"},{"key":"10.1046\/j.1365-2133.1998.02409.x-BIB33|cit33","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0733-8635(18)30454-6","article-title":"Dendritic cells of the skin","volume":"8","author":"Stingl","year":"1990","journal-title":"Dermatol Clin"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1365-2133.1998.02409.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1046\/j.1365-2133.1998.02409.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T20:41:40Z","timestamp":1704314500000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/139\/3\/453\/6683764"}},"subtitle":["IRRITANT-INDUCED LANGERHANS CELL APOPTOSIS IN VIVO"],"short-title":[],"issued":{"date-parts":[[1998,9]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1998,9]]}},"URL":"https:\/\/doi.org\/10.1046\/j.1365-2133.1998.02409.x","relation":{},"ISSN":["0007-0963"],"issn-type":[{"value":"0007-0963","type":"print"}],"subject":[],"published":{"date-parts":[[1998,9]]}}}