{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:35:03Z","timestamp":1761057303833},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":5297,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2001,3]]},"DOI":"10.1046\/j.1365-2133.2001.04092.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T05:35:43Z","timestamp":1047360943000},"page":"597-600","source":"Crossref","is-referenced-by-count":56,"title":["Common variable immunodeficiency treated with a recombinant human IgG, tumour necrosis factor-\u03b1 receptor fusion protein"],"prefix":"10.1093","volume":"144","author":[{"given":"K.J.","family":"Smith","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Skelton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1006\/clim.1999.4725","article-title":"Common variable immunodeficiency: clinical and immunologic features of 248 patients","volume":"92","author":"Cunningham-Rundles","year":"1999","journal-title":"Clin Immunol"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB2","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0167-5699(97)01086-4","article-title":"Common variable immunodeficiency: How many diseases?","volume":"18","author":"Spickett","year":"1997","journal-title":"Immunol Today"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB3","doi-asserted-by":"crossref","first-page":"720","DOI":"10.7326\/0003-4819-118-9-199305010-00011","article-title":"New insights into common variable immunodeficiency","volume":"118","author":"Sneller","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB4","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0090-1229(90)90145-G","article-title":"Classification of patients with common variable immunodeficiency by B-cell secretion of IgM and IgG responses to anti-IgM and interleukin 2","volume":"56","author":"Bryant","year":"1990","journal-title":"Clin Immunol Immunopathol"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1046\/j.1365-2249.1997.d01-993.x","article-title":"Failure in antigen responses in common variable immunodeficiency (CVID) associated with failure in production of antigen-specific memory T\u00a0cells. MRC Immunodeficiency Group","volume":"108","author":"Stagg","year":"1997","journal-title":"Clin Exp Immunol"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB6","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/BF00915297","article-title":"Interleukin 2 correction of defective in vitro T cell mitogenesis in patients with common variable immunodeficiency","volume":"4","author":"Kruger","year":"1984","journal-title":"J Clin Immunol"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB7","first-page":"334","article-title":"Peripheral blood lymphocytes of patients with common variable immunodeficiency produce reduced levels of interleukin-4, interleukin-2, and interferon gamma, but proliferate normally upon activation with mitogens","volume":"78","author":"Pastorelli","year":"1989","journal-title":"Clin Exp Immunol"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB8","doi-asserted-by":"crossref","first-page":"3762","DOI":"10.4049\/jimmunol.144.10.3762","article-title":"Abnormalities of lymphokine gene expression in patients with common variable immunodeficiency","volume":"144","author":"Sneller","year":"1990","journal-title":"J Immunol"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB9","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/0167-5699(89)90323-X","article-title":"The role of lymphokines in common variable hypogammaglobulinemia","volume":"10","author":"Spickett","year":"1989","journal-title":"Immunol Today"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB10","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1182\/blood.V87.2.674.bloodjournal872674","article-title":"Persistent activation of the tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency: possible immunologic and clinical consequences","volume":"87","author":"Aukrust","year":"1996","journal-title":"Blood"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB11","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1159\/000018093","article-title":"Cutaneous granulomatous lesions in common variable immunodeficiency: complete resolution after intravenous immunoglobulins","volume":"198","author":"Pujol","year":"1999","journal-title":"Dermatology"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB12","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/j.1525-1470.1995.tb00147.x","article-title":"Caseating cutaneous granulomas in a child with common variable immunodeficiency","volume":"12","author":"Torrelo","year":"1995","journal-title":"Pediatr Dermatol"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB13","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S0190-9622(18)30762-X","article-title":"Cutaneous granulomas with two clinical presentations in a patient with common variable immunodeficiency","volume":"37","author":"Ziegler","year":"1997","journal-title":"J Am Acad Dermatol"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB14","first-page":"251","article-title":"Sarcoidosis and common variable immunodeficiency: report of 8 cases and review of the literature","volume":"75","author":"Fasano","year":"1996","journal-title":"Cytokine"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB15","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1111\/j.1365-2133.1994.tb06896.x","article-title":"Cutaneous sarcoid-like granulomas in primary immunodeficiency disorder","volume":"130","author":"Levine","year":"1994","journal-title":"Br J Dermatol"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB16","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1182\/blood.V76.10.2046.2046","article-title":"Characterization of common variable immunodeficiency: identification of a subset of patients with distinctive immunophenotype and clinical features","volume":"76","author":"Wright","year":"1990","journal-title":"Blood"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB17","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0954-6111(06)80024-7","article-title":"Speculations on sarcoidosis","volume":"86","author":"O'Conner","year":"1992","journal-title":"Respir Med"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB18","first-page":"775","article-title":"Detection of M. tuberculosis DNA in sarcoidosis: correlation with T-cell response","volume":"79","author":"Grosser","year":"1999","journal-title":"Lab Invest"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB19","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1046\/j.1365-2249.1999.00924.x","article-title":"In vivo modulation of cytokine synthesis by intravenous immunoglobulin","volume":"116","author":"Swell","year":"1999","journal-title":"Clin Exp Immunol"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB20","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0889-857X(05)70025-9","article-title":"Biologic agents and immunotherapy in rheumatoid arthritis","volume":"24","author":"Wallis","year":"1998","journal-title":"Rheum Dis Clin North Am"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB21","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/S0016-5085(99)70224-6","article-title":"Tumor necrosis factor alpha antibody (infliximab) therapy profoundly down-regulates the inflammation in Crohn\u2019s ileocolitis","volume":"116","author":"Baert","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB22","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/00002281-199901000-00015","article-title":"Update on sarcoidosis","volume":"11","author":"Jones","year":"1999","journal-title":"Curr Opin Rheumatol"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB23","doi-asserted-by":"crossref","first-page":"4126","DOI":"10.1016\/S0041-1345(98)01365-7","article-title":"Anti-TNF alpha therapy is useful in rheumatoid arthritis and Crohn\u2019s disease: analysis of the mechanism of action predicts utility in other disease","volume":"30","author":"Feldman","year":"1998","journal-title":"Transplant Proc"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB24","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0149-2918(00)88269-7","article-title":"Etanercept, a novel drug for the treatment of patients with severe, active rheumatoid arthritis","volume":"21","author":"Goldenberg","year":"1999","journal-title":"Clin Ther"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB25","doi-asserted-by":"crossref","first-page":"478","DOI":"10.7326\/0003-4819-130-6-199903160-00004","article-title":"Etanercept therapy in rheumatoid arthritis. A randomized, controlled trial","volume":"130","author":"Moreland","year":"1999","journal-title":"Ann Intern Med"},{"key":"10.1046\/j.1365-2133.2001.04092.x-BIB26","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/S0016-5085(99)70005-3","article-title":"Endoscopic and histological healing with infliximab anti-tumor necrosis factor antibodies in Crohn\u2019s disease: a European multicenter trial","volume":"116","author":"D'Haens","year":"1999","journal-title":"Gastroenterology"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1365-2133.2001.04092.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1046\/j.1365-2133.2001.04092.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T20:55:31Z","timestamp":1682110531000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/144\/3\/597\/6690802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,3]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2001,3]]}},"URL":"https:\/\/doi.org\/10.1046\/j.1365-2133.2001.04092.x","relation":{},"ISSN":["0007-0963","1365-2133"],"issn-type":[{"value":"0007-0963","type":"print"},{"value":"1365-2133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,3]]}}}