{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T17:41:33Z","timestamp":1794591693880,"version":"4.9.1"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2001,12,24]],"date-time":"2001-12-24T00:00:00Z","timestamp":1009152000000},"content-version":"vor","delay-in-days":510,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2000,8]]},"abstract":"<jats:p>We report a case of congenital dyserythropoietic anaemia, type I, with severe pre\u2010 and postnatal manifestations. Exchange transfusions were required for fetal anaemia (3\u00b75\u2003g\/dl) at 28 and 30\u2003weeks of gestation. Transfusions were administered at birth (Caesarean section at week 35) and at regular intervals thereafter. At 14\u2003months, \u03b1\u2010interferon therapy was initiated (10<jats:sup>6<\/jats:sup> units three times a week). This resulted in stabilization of the haemoglobin at or above 11\u2003g\/dl and a reduction in the percentage of erythroblasts with ultrastructurally abnormal heterochromatin. After 9\u2003months, the dose of \u03b1\u2010interferon was decreased to 10<jats:sup>6<\/jats:sup> units twice a week. No relapse of anaemia was noted during an additional 4\u2003months of follow\u2010up.<\/jats:p>","DOI":"10.1046\/j.1365-2141.2000.02168.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T06:27:06Z","timestamp":1047364026000},"page":"420-423","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Severe congenital dyserythropoietic anaemia type I: prenatal management, transfusion support and alpha\u2010interferon therapy"],"prefix":"10.1111","volume":"110","author":[{"given":"N.","family":"Parez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Dommergues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Zupan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Chambost","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. B.","family":"Fieschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Delaunay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Mi\u00e9lot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. M.","family":"Cramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.\u2010P.","family":"Dommergues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. N.","family":"Wickramasinghe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Tchernia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2001,12,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(98)70034-4"},{"key":"e_1_2_5_3_1","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1182\/blood.V94.3.1139.415a35c_1139_1141","article-title":"Genetic heterogeneity of congenital dyserythropoietic anemia type I","volume":"94","author":"Hodges V.M.","year":"1999","journal-title":"Blood"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1995.tb08442.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004310050310"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1998.01071.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(97)70130-6"},{"key":"e_1_2_5_8_1","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1182\/blood.V87.5.1763.1763","article-title":"Clinical features and studies of erythropoiesis in Israel Bedouins with congenital dyserythropoietic anaemia type I","volume":"87","author":"Tamary H.","year":"1996","journal-title":"Blood"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1086\/301834"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1997.2513065.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0268-960X(98)90016-9"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1997.1993016.x"},{"key":"e_1_2_5_13_1","first-page":"4422","article-title":"High adenosine deaminase level among healthy probands of Diamond Blackfan anemia (DBA) cosegregates with the DBA gene region on chromosome 19q13. The DBA Working Group of Soci\u00e9t\u00e9 d'Immunologie P\u00e9diatrique (SHIP)","volume":"92","author":"Willig T.N.","year":"1998","journal-title":"Blood"}],"container-title":["British Journal of Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1365-2141.2000.02168.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1365-2141.2000.02168.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1046\/j.1365-2141.2000.02168.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T16:30:44Z","timestamp":1698597044000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1046\/j.1365-2141.2000.02168.x"}},"subtitle":["SHORT REPORT"],"short-title":[],"issued":{"date-parts":[[2000,8]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2000,8]]}},"alternative-id":["10.1046\/j.1365-2141.2000.02168.x"],"URL":"https:\/\/doi.org\/10.1046\/j.1365-2141.2000.02168.x","archive":["Portico"],"relation":{},"ISSN":["0007-1048","1365-2141"],"issn-type":[{"value":"0007-1048","type":"print"},{"value":"1365-2141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,8]]},"assertion":[{"value":"2001-12-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}