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These included <jats:italic>Candida<\/jats:italic> (<jats:italic>n<\/jats:italic>\u2003=\u200394), <jats:italic>Aspergillus<\/jats:italic> (<jats:italic>n<\/jats:italic>\u2003=\u200391), <jats:italic>Zygomycetes<\/jats:italic> (<jats:italic>n<\/jats:italic>\u2003=\u200334), <jats:italic>Cryptococcus<\/jats:italic> (<jats:italic>n<\/jats:italic>\u2003=\u20037), <jats:italic>Trichosporon<\/jats:italic> (<jats:italic>n<\/jats:italic>\u2003=\u200311), <jats:italic>Fusarium<\/jats:italic> (<jats:italic>n<\/jats:italic>\u2003=\u20031), and unknown fungi (<jats:italic>n<\/jats:italic>\u2003=\u200320). Of the 94 patients with invasive candidiasis, 20 had positive blood cultures. Of the 11 patients with invasive trichosporonosis, seven had positive blood cultures. The sensitivities of blood cultures were 1\u00b71%, 0% and 14% for detecting invasive aspergillosis, zygomycosis and cryptococcosis respectively. Multiple regression analysis showed a significant correlation between results of <jats:italic>Candida<\/jats:italic> blood cultures and some variables, including prophylactic use of absorbable antifungals (<jats:italic>P<\/jats:italic>\u2003=\u20030\u00b70181) and infection by <jats:italic>Candida albicans<\/jats:italic> (<jats:italic>P<\/jats:italic>\u2003= 0\u00b70086). The sensitivity of blood cultures decreased when patients received antifungal chemoprophylaxis. Unless these agents are inactivated in culture bottles, conventional blood cultures might produce false\u2010negative results.<\/jats:p>","DOI":"10.1046\/j.1365-2141.2002.03414.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T06:44:05Z","timestamp":1047365045000},"page":"40-46","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":101,"title":["Effect of fluconazole prophylaxis on fungal blood cultures: an autopsy\u2010based study involving 720 patients with haematological malignancy"],"prefix":"10.1111","volume":"117","author":[{"given":"Masahiro","family":"Kami","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Utako","family":"Machida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuko","family":"Okuzumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoko","family":"Matsumura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin\u2010ichiro","family":"Mori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Hori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Kashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinobu","family":"Kanda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoichi","family":"Takaue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisashi","family":"Sakamaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisamaru","family":"Hirai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Yoneyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshitomo","family":"Mutou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,3,25]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1128\/jcm.15.5.860-864.1982","article-title":"Comparison of recovery of organisms from blood cultures diluted 10% (volume\/volume) and 20% (volume \/volume)","volume":"15","author":"Auckenthaler R.","year":"1982","journal-title":"Journal of Clinical Microbiology"},{"key":"e_1_2_5_3_1","first-page":"675","article-title":"Autopsy\u2010identified infections among bone marrow transplant recipients: a clinico\u2010pathologic study of 56 patients. 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