{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T01:39:49Z","timestamp":1792114789194,"version":"4.4.0"},"reference-count":42,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2002,6,10]],"date-time":"2002-06-10T00:00:00Z","timestamp":1023667200000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2002,6]]},"abstract":"<jats:p><jats:bold>Summary.<\/jats:bold>Between 1982 and 2000, 172 patients with acute myelogenous leukaemia (AML) received haematopoietic stem cell transplants (SCT) from related (<jats:italic>n<\/jats:italic>= 132) or unrelated (<jats:italic>n<\/jats:italic>\u2003=\u200340) donors at four Austrian transplant centres and their results were reported to the Austrian Stem Cell Transplantation Registry. Conditioning for SCT consisted of cyclophosphamide and total body irradiation in 156 (91%) patients. Graft\u2010versus\u2010host disease (GVHD) prophylaxis was with standard cyclosporine and methotrexate in 95 (55%) patients. Median post\u2010transplant follow\u2010up was 5\u00b76\u2003years (range, 0\u00b72\u2010\u201016\u00b77). Multivariate analysis of transplant\u2010related mortality (TRM) identified four variables associated with a lower risk: disease status of first complete remission (CR) at SCT, patient age of 45\u2003years and younger, transplant performed during or after 1995, and lack of acute GVHD. Variables associated with significantly improved leukaemia\u2010free survival were: bone marrow as the stem cell source, disease status of first CR at SCT, and occurrence of chronic GVHD. In multivariate analysis, transplantation performed during or after 1995, first CR at SCT, occurrence of limited chronic GVHD and lack of acute GVHD grades III to IV were associated with increased overall survival. Based on these analyses, options for the improvement of results obtained with allogeneic SCT in patients with AML could be defined.<\/jats:p>","DOI":"10.1046\/j.1365-2141.2002.03532.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T06:45:37Z","timestamp":1047365137000},"page":"914-923","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Factors affecting long\u2010term outcome after allogeneic haematopoietic stem cell transplantation for acute myelogenous leukaemia: a retrospective study of 172 adult patients reported to the Austrian Stem Cell Transplantation Registry"],"prefix":"10.1111","volume":"117","author":[{"given":"Hildegard 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