{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T15:22:16Z","timestamp":1774538536224,"version":"3.50.1"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[1998,2,1]],"date-time":"1998-02-01T00:00:00Z","timestamp":886291200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1998,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Incidence and pattern of lymph node metastasis (LNM) were evaluated in 35 patients who underwent primary surgery for papillary thyroid carcinoma.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Total thyroidectomy with systematic cervicocentral lymphadenectomy was performed routinely. Additionally, 22 patients underwent lymphadenectomy of the ipsilateral cervicolateral compartment. Sternotomy was performed in four patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Primary tumour status was: pT1, n = 7; pT2, n = 12; pT3, n = 4; pT4, n = 12. Twenty-four patients had LNM in the ipsilateral cervicocentral compartment (pT1, n = 2; pT2, n = 8; pT3, n = 4; pT4, n = 10). Nineteen had LNM in the ipsilateral cervicolateral compartment (pT1, n = 4; pT2, n = 6; pT3, n = 2; pT4, n = 7). Contralateral cervicocentral LNM was restricted to patients with pT3 tumours (n = 2) or pT4 tumours (n = 3). No patient had LNM in the contralateral cervicolateral compartment. Only one patient (pT3 tumour) had mediastinal LNM.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The cervicocentral compartment was most commonly involved with metastases, although the ipsilateral cervicolateral compartment was almost as often affected. In some patients ipsilateral cervicolateral LNM was present in the absence of cervicocentral LNM. Contralateral cervicolateral and upper mediastinal LNM, however, were rare. This study helps to plan radical surgery for papillary thyroid carcinoma.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1046\/j.1365-2168.1998.00510.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T07:00:00Z","timestamp":1047366000000},"page":"252-254","source":"Crossref","is-referenced-by-count":170,"title":["Pattern of lymph node metastases in papillary thyroid carcinoma"],"prefix":"10.1093","volume":"85","author":[{"given":"O","family":"Gimm","sequence":"first","affiliation":[{"name":"Department of General Surgery, Martin-Luther-University Halle-Wittenberg , Halle\/Saale,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F W","family":"Rath","sequence":"additional","affiliation":[{"name":"Department of Pathology, Martin-Luther-University Halle-Wittenberg , Halle\/Saale,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Dralle","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Martin-Luther-University Halle-Wittenberg , Halle\/Saale,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1998,2,1]]},"reference":[{"key":"2024092913593227600_bib1","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1097\/00000658-198209000-00016","article-title":"Total thyroidectomy: the treatment of choice for patients with differentiated thyroid cancer","volume":"196","author":"Clark","year":"1982","journal-title":"Ann Surg"},{"key":"2024092913593227600_bib2","first-page":"957","article-title":"Biologic considerations and operative strategy in papillary thyroid carcinoma: arguments against the routine performance of total thyroidectomy","volume":"96","author":"Cohn","year":"1984","journal-title":"Surgery"},{"key":"2024092913593227600_bib3","doi-asserted-by":"crossref","first-page":"2691","DOI":"10.1002\/1097-0142(19850601)55:11<2691::AID-CNCR2820551126>3.0.CO;2-Y","article-title":"The advantages of subtotal thyroidectomy and suppression of TSH in the primary treatment of papillary carcinoma of the thyroid","volume":"55","author":"Crile","year":"1985","journal-title":"Cancer"},{"key":"2024092913593227600_bib4","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/BF00348202","article-title":"Does the method of management of papillary thyroid carcinoma make a difference in outcome?","volume":"18","author":"DeGroot","year":"1994","journal-title":"World J Surg"},{"key":"2024092913593227600_bib5","first-page":"118","article-title":"On the significance of lymph-node metastases of differentiated thyroid carcinoma and patient survival (a quantitative approach by meta-analysis and multivariate analyses of retrospective studies)","volume":"101","author":"Goretzki","year":"1993","journal-title":"Exp Clin Endocrinol"},{"key":"2024092913593227600_bib6","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0002-9610(78)90209-X","article-title":"Significance of lymph node metastases in differentiated thyroid cancer","volume":"136","author":"Harwood","year":"1978","journal-title":"Am J Surgl"},{"key":"2024092913593227600_bib7","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/S0002-9610(05)80710-X","article-title":"Prognostic significance of cervical lymph node metastases in differentiated thyroid cancer","volume":"164","author":"Sellers","year":"1992","journal-title":"Am J Surg"},{"key":"2024092913593227600_bib8","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/BF00353765","article-title":"Prognostic significance and surgical management of locoregional lymph node metastases in papillary thyroid cancer","volume":"18","author":"Scheumann","year":"1994","journal-title":"World J Surg"},{"key":"2024092913593227600_bib9","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0002-9610(91)90147-6","article-title":"Prospective management of nodal metastases in differentiated thyroid cancer","volume":"162","author":"McHenry","year":"1991","journal-title":"Am J Surg"},{"key":"2024092913593227600_bib10","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/BF03346863","article-title":"Papillary thyroid carcinoma: occurrence and types of lymph node metastases","volume":"14","author":"Ahuja","year":"1991","journal-title":"J Endocrinol Invest"},{"key":"2024092913593227600_bib11","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1002\/1097-0142(197011)26:5<1053::AID-CNCR2820260513>3.0.CO;2-X","article-title":"Papillary carcinoma of the thyroid. 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