{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T03:11:27Z","timestamp":1785726687238,"version":"3.56.0"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[1998,1,1]],"date-time":"1998-01-01T00:00:00Z","timestamp":883612800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1998,1,1]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Marsupialization of anal fistulotomy wounds leaves less raw unepithelialized tissue to granulate and may improve wound healing.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Some 103 consecutive patients with uncomplicated intersphincteric or trans-sphincteric fistula in ano were recruited into a randomized controlled trial. Fistula tracts were identified and laid open under general anaesthesia. The patients were randomized to have either the wounds left open (LO group) or wound edges marsupialized to the fistula tract with interrupted absorbable sutures (MS group). Anal manometry was performed before operation, and 6 weeks and 3 months after surgery.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Some 52 patients were randomized to the LO group and 51 to the MS group. There were no differences in the age, sex, fistula type and fistula length distribution between the groups. Mean follow-up times were 9 and 10\u00b72 months respectively. Wounds in the MS group healed faster (mean(s.e.m.) 6\u00b70 (0\u00b74) weeks) than those in the LO group (10\u00b70(0\u00b75) weeks) (P&lt;0\u00b7001). Only one patient (2 per cent) in the MS group was incontinent of liquids after operation compared with six (12 per cent) in the LO group. There was less impairment in maximum anal squeeze pressure at 3 months after marsupialization compared with leaving fistulotomy wounds open (P&lt;0\u00b705). Apart from a slightly longer operative time required for marsupialization, the hospitalization and complication rates were the same.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Anal fistulotomy wounds healed faster after marsupialization. Anal squeeze pressures were better preserved and this may improve anal continence.<\/jats:p>\n <\/jats:sec>","DOI":"10.1046\/j.1365-2168.1998.00529.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T06:58:10Z","timestamp":1047365890000},"page":"105-107","source":"Crossref","is-referenced-by-count":79,"title":["Marsupialization of fistulotomy wounds improves healing: a randomized controlled trial"],"prefix":"10.1093","volume":"85","author":[{"given":"Y-H","family":"Ho","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital , Outram Road, , 169 608","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital , Outram Road, , 169 608","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A F P K","family":"Leong","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital , Outram Road, , 169 608","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Seow-Choen","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital , Outram Road, , 169 608","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1998,1,1]]},"reference":[{"key":"2024092920043003100_bib1","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1002\/bjs.1800721211","article-title":"To lay open or excise a fistula-in-ano: a randomized trial","volume":"72","author":"Kronborg","year":"1985","journal-title":"Br J Surg"},{"key":"2024092920043003100_bib2","first-page":"268","article-title":"Fistulotomy and marsupialisation for simple fistula-in-ano","volume":"33","author":"Yang","year":"1992","journal-title":"Singapore Med J"},{"key":"2024092920043003100_bib3","first-page":"22","volume-title":"Current Therapy in Colon and Rectal Surgery","author":"Belliveau","year":"1990"},{"key":"2024092920043003100_bib4","first-page":"263","article-title":"Computerised 3-dimensional vector volume analysis \u2013 the role of a new method for assessing anal sphincter competence","volume":"21","author":"Ho","year":"1992","journal-title":"Ann Acad Med Singapore"},{"key":"2024092920043003100_bib5","first-page":"244","article-title":"Current value of anorectal physiology and biofeedback in clinical practice","volume":"18","author":"Ho","year":"1995","journal-title":"Asian Journal of Surgery"},{"key":"2024092920043003100_bib6","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/BF01648418","article-title":"Fistula-in-ano is usually simple to manage surgically","volume":"1","author":"Schouler","year":"1986","journal-title":"Int J Colorectal Dis"},{"key":"2024092920043003100_bib7","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/BF02554037","article-title":"Results of treatment of fistula-in-ano","volume":"28","author":"Vasilevsky","year":"1985","journal-title":"Dis Colon Rectum"},{"key":"2024092920043003100_bib8","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1007\/BF02560157","article-title":"Fistula-in-ano. A manometric study","volume":"26","author":"Belliveau","year":"1983","journal-title":"Dis Colon Rectum"},{"key":"2024092920043003100_bib9","first-page":"7","article-title":"Fistula-in-ano, an investigation of human foetal anal ducts and intramuscular glands and a clinical study of 150 patients","volume":"383","author":"Lilius","year":"1968","journal-title":"Acta Chirurgica Scandinavica Supplementum"},{"key":"2024092920043003100_bib10","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1007\/BF02257781","article-title":"Continence disorders after anal fistulotomy","volume":"37","author":"van-Tets","year":"1994","journal-title":"Dis Colon Rectum"},{"key":"2024092920043003100_bib11","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1007\/BF02052593","article-title":"Is simple fistula-in-ano simple?","volume":"37","author":"Sangwan","year":"1994","journal-title":"Dis Colon Rectum"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1365-2168.1998.00529.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/85\/1\/105\/59431551\/bjs375.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/85\/1\/105\/59431551\/bjs375.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,29]],"date-time":"2024-09-29T20:04:42Z","timestamp":1727640282000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/85\/1\/105\/6269921"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,1,1]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1998,1,1]]},"published-print":{"date-parts":[[1998,1,1]]}},"URL":"https:\/\/doi.org\/10.1046\/j.1365-2168.1998.00529.x","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1998,1]]},"published":{"date-parts":[[1998,1,1]]}}}