{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:25:38Z","timestamp":1761560738404},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2000,3,1]],"date-time":"2000-03-01T00:00:00Z","timestamp":951868800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The aim was to perform a prospective randomized study in patients with chronic gastro-oesophageal reflux treated either by total fundoplication or calibration of the cardia with posterior gastropexy. Late follow-up considered subjective and objective parameters, and related outcome to the presence of Barrett's oesophagus.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A total of 164 patients were randomized to fundoplication (n = 76) or calibration of the cardia (n = 88). They were evaluated by clinical questionnaire, upper gastrointestinal endoscopy with biopsies, oesophageal manometry and gastro-oesophageal reflux studies, including scintigraphy and 24-h oesophageal pH monitoring.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>There were no operative deaths. There was 95 per cent follow-up at a mean of 85 months. The mean recurrence rate for both operations was near 40 per cent at 10 years, but patients without Barrett's oesophagus had a recurrence rate after both operations of around 23 per cent compared with 83 per cent after 10 years for those with Barrett's oesophagus (P &amp;lt; 0\u00b70001). Low-grade dysplasia developed in 13 per cent of the patients with Barrett's oesophagus. There were significant differences in all objective parameters in a comparison of patients with Visick I or II and those with Visick III or IV disease at the late assessment.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Both total fundoplication and calibration of the cardia with posterior gastropexy had similar subjective and objective late results. However, results were significantly worse in patients with Barrett's oesophagus.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1046\/j.1365-2168.2000.01296.x","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T10:33:31Z","timestamp":1027679611000},"page":"289-297","source":"Crossref","is-referenced-by-count":49,"title":["Late results of a randomized clinical trial comparing total fundoplication versus calibration of the cardia with posterior gastropexy"],"prefix":"10.1093","volume":"87","author":[{"given":"A","family":"Csendes","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Chile Hospital , Santiago,","place":["Chile"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Burdiles","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Chile Hospital , Santiago,","place":["Chile"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O","family":"Korn","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Chile Hospital , Santiago,","place":["Chile"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Braghetto","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Chile Hospital , Santiago,","place":["Chile"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Huertas","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Chile Hospital , Santiago,","place":["Chile"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Rojas","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Chile Hospital , Santiago,","place":["Chile"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2000,3,1]]},"reference":[{"key":"2024093005182050100_bib1","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1136\/gut.38.4.481","article-title":"Natural history of reflux oesophagitis. 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