{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T17:05:21Z","timestamp":1792170321712,"version":"4.4.0"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2000,4,1]],"date-time":"2000-04-01T00:00:00Z","timestamp":954547200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Application of a topical anaesthetic agent may facilitate infiltration of local anaesthetic at haemorrhoidectomy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A randomized clinical trial of 53 consecutive patients requiring elective haemorrhoidectomy was carried out. One group underwent haemorrhoidectomy under general anaesthesia, while the second group had topical anaesthetic cream (containing lignocaine and prilocaine) applied followed by local anaesthetic infiltration for surgical anaesthesia.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>There were no differences between the two groups in terms of operating time, postoperative pain, nausea or vomiting, pain-free interval after operation, analgesic requirements or patients' satisfaction with the method of anaesthesia. Postoperative oxygen saturation and pulse rate were similar in the two groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Topical anaesthetic and local anaesthesia can be used effectively for haemorrhoidectomy and provide an alternative to general anaesthesia.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1046\/j.1365-2168.2000.01411.x","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T10:33:31Z","timestamp":1027679611000},"page":"410-413","source":"Crossref","is-referenced-by-count":39,"title":["Randomized clinical trial of haemorrhoidectomy under a mixture of local anaesthesia <i>versus<\/i> general anaesthesia"],"prefix":"10.1093","volume":"87","author":[{"given":"K S","family":"Ho","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital , Outram Road, 169608","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K W","family":"Eu","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital , Outram Road, 169608","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S M","family":"Heah","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital , Outram Road, 169608","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Seow-Choen","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital , Outram Road, 169608","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y W","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Singapore General Hospital , Outram Road, 169608","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2000,4,1]]},"reference":[{"key":"2024093005180674700_bib1","doi-asserted-by":"crossref","first-page":"126","DOI":"10.2165\/00003495-199346010-00008","article-title":"Eutectic lidocaine\/prilocaine cream. A review of the topical anaesthetic\/analgesic efficacy of a eutectic mixture of local anesthetics (EMLA)","volume":"46","author":"Buckley","year":"1993","journal-title":"Drugs"},{"key":"2024093005180674700_bib2","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/j.1365-2133.1991.tb14751.x","article-title":"Ablation of whiteheads by cautery under topical anaesthesia","volume":"125","author":"Pepall","year":"1991","journal-title":"Br J Dermatol"},{"key":"2024093005180674700_bib3","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1136\/bjo.78.3.209","article-title":"Percutaneous anaesthesia with a lignocaine\u2013prilocaine cream (Emla) for eyelid skin surgery","volume":"78","author":"Gotsis","year":"1994","journal-title":"Br J Opthalmol"},{"key":"2024093005180674700_bib4","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1111\/j.1365-2273.1992.tb01720.x","article-title":"Myringoplasty under local anaesthesia: day case surgery","volume":"17","author":"Kaddour","year":"1992","journal-title":"Clin Otolaryngol"},{"key":"2024093005180674700_bib5","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0266-4356(92)90146-A","article-title":"Topical application of 5% eutectic mixture of lignocaine and prilocaine (EMLA) before removal of arch bars","volume":"30","author":"Pere","year":"1992","journal-title":"Br J Oral Maxillofac Surg"},{"key":"2024093005180674700_bib6","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1111\/j.1464-410X.1995.tb07797.x","article-title":"Cream anaesthesia for frenuloplasty","volume":"76","author":"Brough","year":"1995","journal-title":"Br J Urol"},{"key":"2024093005180674700_bib7","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1007\/BF02251970","article-title":"Prospective randomized trial comparing pain and clinical function after conventional scissors excision\/ligation vs. diathermy excision without ligation for symptomatic prolapsed haemorrhoids","volume":"35","author":"Seow-Choen","year":"1992","journal-title":"Dis Colon Rectum"},{"key":"2024093005180674700_bib8","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1002\/bjs.1800810255","article-title":"Comparison of emergency and elective haemorrhoidectomy","volume":"81","author":"Eu","year":"1994","journal-title":"Br J Surg"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1365-2168.2000.01411.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1365-2168.2000.01411.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/87\/4\/410\/59438463\/bjs432.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/87\/4\/410\/59438463\/bjs432.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T05:18:37Z","timestamp":1727673517000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/87\/4\/410\/6269090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,4,1]]},"references-count":8,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2000,4,1]]},"published-print":{"date-parts":[[2000,4,1]]}},"URL":"https:\/\/doi.org\/10.1046\/j.1365-2168.2000.01411.x","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2000,4]]},"published":{"date-parts":[[2000,4,1]]}}}