{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T07:45:36Z","timestamp":1789371936745,"version":"build-2803163510"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Peritoneal mesothelioma is a rare peritoneal malignancy, representing approximately one-third of all mesotheliomas. It is regarded as a universally fatal cancer with few treatment options.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Records of 33 patients with peritoneal mesothelioma were reviewed retrospectively. Demographic, clinical and quantitative prognostic indicators were evaluated and analysed statistically using survival as endpoint. Patients were treated by a uniform strategy involving cytoreductive surgery with peritonectomy procedures and perioperative intraperitoneal chemotherapy (cisplatin, doxorubicin).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>There were ten women and 23 men; mean age was 53\u00b70 years. Asbestos exposure was recorded in five patients and a family history of cancer in 13. Presentation was mainly abdominal distension and pain. Median survival was 31\u00b70 months; overall projected survival at 3 years was 56 per cent. The most significant positive predictive factors of survival were: female sex (P = 0\u00b7003), low prior surgical score (P = 0\u00b7002), completeness of cytoreduction (P = 0\u00b70002) and second-look surgery (P = 0\u00b7019). The morbidity rate for this combined treatment was 33 per cent and the perioperative mortality rate was 3 per cent.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Although peritoneal mesothelioma is rare, progress in its management has occurred. Survival has been extended and selection factors by which patients may be allocated to aggressive management strategies have been defined.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1046\/j.1365-2168.2000.01571.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T07:12:14Z","timestamp":1047366734000},"page":"1587-1593","source":"Crossref","is-referenced-by-count":127,"title":["Results of treatment of 33 patients with peritoneal mesothelioma"],"prefix":"10.1093","volume":"87","author":[{"given":"G","family":"Sebbag","sequence":"first","affiliation":[{"name":"Washington Cancer Institute, Washington Hospital Center , Washington, DC,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Pathology, Washington Hospital Center , Washington, DC,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B M","family":"Shmookler","sequence":"additional","affiliation":[{"name":"Department of Pathology, Washington Hospital Center , Washington, DC,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Chang","sequence":"additional","affiliation":[{"name":"Westat , Rockville, Maryland,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P H","family":"Sugarbaker","sequence":"additional","affiliation":[{"name":"Washington Cancer Institute, Washington Hospital Center , Washington, DC,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2000,11,1]]},"reference":[{"key":"2024093005095951600_bib1","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1002\/1097-0142(19921215)70:12<2969::AID-CNCR2820701239>3.0.CO;2-A","article-title":"New strategies are needed in diffuse malignant mesothelioma","volume":"70","author":"Sridhar","year":"1992","journal-title":"Cancer"},{"key":"2024093005095951600_bib2","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1200\/JCO.1988.6.1.147","article-title":"Malignant mesothelioma: prognostic variables in a registry of 180 patients, the Dana-Farber Cancer Institute and Brigham and Women's Hospital experience over two decades","volume":"6","author":"Antman","year":"1988","journal-title":"J Clin Oncol"},{"key":"2024093005095951600_bib3","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1001\/archsurg.1990.01410230071012","article-title":"Primary malignant peritoneal mesothelioma. A report of seven cases and a review of the literature","volume":"125","author":"Asensio","year":"1990","journal-title":"Arch Surg"},{"key":"2024093005095951600_bib4","first-page":"260","article-title":"Diffuse pleural mesothelioma and asbestos exposure in the North Western Cape Province","volume":"17","author":"Wagner","year":"1960","journal-title":"British Journal of Industrial Medicine"},{"key":"2024093005095951600_bib5","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1002\/1097-0142(19840901)54:5<951::AID-CNCR2820540536>3.0.CO;2-A","article-title":"Non-asbestos-related malignant mesothelioma. A review","volume":"54","author":"Peterson","year":"1984","journal-title":"Cancer"},{"key":"2024093005095951600_bib6","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/00000658-199501000-00004","article-title":"Peritonectomy procedures","volume":"221","author":"Sugarbaker","year":"1995","journal-title":"Ann Surg"},{"key":"2024093005095951600_bib7","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1002\/(SICI)1098-2388(199804\/05)14:3<254::AID-SSU10>3.0.CO;2-U","article-title":"Intraperitoneal chemotherapy and cytoreductive surgery for the prevention and treatment of peritoneal carcinomatosis and sarcomatosis","volume":"14","author":"Sugarbaker","year":"1998","journal-title":"Semin Surg Oncol"},{"key":"2024093005095951600_bib8","first-page":"366","volume-title":"Peritoneal Carcinomatosis: Principles of Management","author":"Jacquet","year":"1996"},{"key":"2024093005095951600_bib9","first-page":"81","article-title":"Elective surgery in recurrent colon cancer with peritoneal seeding: when to and when not to proceed","volume":"20","author":"Esquivel","year":"1999","journal-title":"G Chir"},{"key":"2024093005095951600_bib10","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0021-9681(60)90137-5","article-title":"Appraisal of methods for the study of chemotherapy of cancer in man: comparative therapeutic trial of nitrogen mustard and triethylene thiophosphoramide","volume":"11","author":"Zubrod","year":"1960","journal-title":"J Chronic Dis"},{"key":"2024093005095951600_bib11","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/978-1-4613-1245-1_17","article-title":"Peritoneal mesothelioma: treatment approach based on natural history","volume":"81","author":"Averbach","year":"1996","journal-title":"Cancer Treat Res"},{"key":"2024093005095951600_bib12","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/978-1-4613-1245-1_3","volume-title":"Peritoneal Carcinomatosis: Drugs and Diseases","author":"Stephens","year":"1996"},{"key":"2024093005095951600_bib13","first-page":"1164","volume-title":"Cancer Treatment","author":"National Cancer Institute \/ Southwest Oncology Group","year":"1995","edition":"IVth"},{"key":"2024093005095951600_bib14","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Non-parametric estimation for incomplete observations","volume":"53","author":"Kaplan","year":"1958","journal-title":"J Am Stat Assoc"},{"key":"2024093005095951600_bib15","doi-asserted-by":"crossref","first-page":"185","DOI":"10.2307\/2344317","article-title":"Asymptotically efficient rank invariant test procedures","volume":"135","author":"Peto","year":"1972","journal-title":"J R Stat Soc A"},{"key":"2024093005095951600_bib16","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/path.1700120212","article-title":"A malignant tumor arising from the endothelium of the peritoneum, and producing a mucoid ascitic fluid","volume":"12","author":"Miller","year":"1908","journal-title":"J Pathol Bacteriol"},{"key":"2024093005095951600_bib17","first-page":"25","volume-title":"Malignant Mesothelioma","author":"Whitaker","year":"1992"},{"key":"2024093005095951600_bib18","first-page":"270","article-title":"Ascites as a result of peritoneal mesotheliomas in a horse","volume":"24","author":"Harps","year":"1996","journal-title":"Tierarztl Prax"},{"key":"2024093005095951600_bib19","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.1600-0684.1999.tb00261.x","article-title":"Spontaneous pericardial mesothelioma in a rhesus monkey","volume":"28","author":"Chandra","year":"1999","journal-title":"J Med Primatol"},{"key":"2024093005095951600_bib20","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.1748-5827.1999.tb03105.x","article-title":"Pericardial mesothelioma in a dog: long-term survival after pericardiectomy in combination with chemotherapy","volume":"40","author":"Closa","year":"1999","journal-title":"J Small Anim Pract"},{"key":"2024093005095951600_bib21","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1136\/thx.52.6.507","article-title":"Malignant mesothelioma in southeast England: clinicopathological experience of 272 cases","volume":"52","author":"Yates","year":"1997","journal-title":"Thorax"},{"key":"2024093005095951600_bib22","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1093\/oxfordjournals.aje.a009093","article-title":"Analysis of current trends in United States mesothelioma incidence","volume":"145","author":"Price","year":"1997","journal-title":"Am J Epidemiol"},{"key":"2024093005095951600_bib23","first-page":"31","volume-title":"Atlas of Tumor Pathology. Tumors of the Serosal Membranes","author":"Battifora","year":"1995"},{"key":"2024093005095951600_bib24","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/978-1-4613-1245-1_18","volume-title":"Peritoneal Carcinomatosis: Drugs and Diseases","author":"Kass","year":"1996"},{"key":"2024093005095951600_bib25","first-page":"94","volume-title":"Atlas of Tumor Pathology. Tumors of the Serosal Membranes","author":"Battifora","year":"1995"},{"key":"2024093005095951600_bib26","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1002\/1097-0142(197309)32:3<656::AID-CNCR2820320319>3.0.CO;2-U","article-title":"Long-term survival in patients with malignant peritoneal mesothelioma treated with irradiation","volume":"32","author":"Rogoff","year":"1973","journal-title":"Cancer"},{"key":"2024093005095951600_bib27","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1002\/1097-0142(1955)8:3<478::AID-CNCR2820080307>3.0.CO;2-4","article-title":"Treatment of peritoneal mesothelioma with radioactive colloidal gold. Report of a case","volume":"8","author":"Rose","year":"1955","journal-title":"Cancer"},{"key":"2024093005095951600_bib28","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1002\/(SICI)1096-9098(199901)70:1<6::AID-JSO2>3.0.CO;2-X","article-title":"Clinical picture, response to therapy, and survival of women with diffuse malignant peritoneal mesothelioma","volume":"70","author":"Eltabbakh","year":"1999","journal-title":"J Surg Oncol"},{"key":"2024093005095951600_bib29","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/BF01225271","article-title":"Efficacy of cisplatin-based intraperitoneal chemotherapy as treatment of malignant peritoneal mesothelioma","volume":"118","author":"Markman","year":"1992","journal-title":"J Cancer Res Clin Oncol"},{"key":"2024093005095951600_bib30","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s002920050340","article-title":"Peritoneal mesothelioma \u2013 incidence and etiology","volume":"20","author":"Neumann","year":"1999","journal-title":"Pathologe"},{"key":"2024093005095951600_bib31","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1007\/s10434-999-0582-6","article-title":"Treatment of primary peritoneal mesothelioma by continuous hyperthermic peritoneal perfusion (CHPP)","volume":"6","author":"Park","year":"1999","journal-title":"Ann Surg Oncol"},{"key":"2024093005095951600_bib32","first-page":"3799","article-title":"Combination chemotherapy with cisplatin and\/or doxorubicin in malignant mesothelioma. A retrospective study","volume":"17","author":"Tsavaris","year":"1997","journal-title":"Anticancer Res"},{"key":"2024093005095951600_bib33","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/S0016-5085(19)33323-2","article-title":"Peritoneal mesothelioma","volume":"63","author":"Moertel","year":"1972","journal-title":"Gastroenterology"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1365-2168.2000.01571.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1365-2168.2000.01571.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/87\/11\/1587\/59438335\/bjs69.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/87\/11\/1587\/59438335\/bjs69.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T05:11:12Z","timestamp":1727673072000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/87\/11\/1587\/6268611"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,11,1]]},"references-count":33,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2000,11,1]]},"published-print":{"date-parts":[[2000,11,1]]}},"URL":"https:\/\/doi.org\/10.1046\/j.1365-2168.2000.01571.x","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2000,11]]},"published":{"date-parts":[[2000,11,1]]}}}