{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T15:25:48Z","timestamp":1765293948839},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2002,9,1]],"date-time":"2002-09-01T00:00:00Z","timestamp":1030838400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2002,11,29]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The choice of surgical strategy for patients with adenocarcinoma of the oesophagogastric junction is controversial. This study was performed to analyse the surgical results of a 20-year experience with these lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From January 1981 to January 2001, 126 patients with adenocarcinoma of the cardia underwent resection in the authors' institution. The treatment of choice was oesophagectomy for type I tumours, and extended gastrectomy for type II and III lesions. Morbidity, mortality and survival were determined retrospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty-six patients (44\u00b74 per cent) had type I tumours, 44 (34\u00b79 per cent) type II and 26 (20\u00b76 per cent) type III. Primary resection was performed in 113 patients (89\u00b77 per cent). Oesophagectomy with resection of the proximal stomach was carried out in 65 patients (51\u00b76 per cent) and extended total gastrectomy with transhiatal resection of the distal oesophagus in 61 (48\u00b74 per cent). In-hospital mortality and morbidity rates were 4\u00b78 and 34\u00b71 per cent respectively. The overall 3- and 5-year survival rates were 40\u00b79 and 25\u00b71 per cent respectively, and were not affected by the surgical approach. Survival was significantly associated with R0 resection, pathological node-positive category, postoperative complications and tumour differentiation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Postoperative mortality, morbidity and long-term survival did not appear to be affected by surgical approach. Further prospective studies are needed to confirm the equivalence between transthoracic and transabdominal approaches.<\/jats:p><\/jats:sec>","DOI":"10.1046\/j.1365-2168.2002.02185.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T07:30:23Z","timestamp":1047367823000},"page":"1156-1163","source":"Crossref","is-referenced-by-count":81,"title":["Surgical management of and long-term survival after adenocarcinoma of the cardia"],"prefix":"10.1093","volume":"89","author":[{"given":"C","family":"Mariette","sequence":"first","affiliation":[{"name":"Service de Chirurgie Digestive et G\u00e9n\u00e9rale, H\u00f4pital Claude Huriez\u2014Centre Hospitalier Regional Universitaire, Place de Verdun, 59037 Lille Cedex, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Castel","sequence":"additional","affiliation":[{"name":"Service de Chirurgie Digestive et G\u00e9n\u00e9rale, H\u00f4pital Claude Huriez\u2014Centre Hospitalier Regional Universitaire, Place de Verdun, 59037 Lille Cedex, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Toursel","sequence":"additional","affiliation":[{"name":"Service de Chirurgie Digestive et G\u00e9n\u00e9rale, H\u00f4pital Claude Huriez\u2014Centre Hospitalier Regional Universitaire, Place de Verdun, 59037 Lille Cedex, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Fabre","sequence":"additional","affiliation":[{"name":"Service de Chirurgie Digestive et G\u00e9n\u00e9rale, H\u00f4pital Claude Huriez\u2014Centre Hospitalier Regional Universitaire, Place de Verdun, 59037 Lille Cedex, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J M","family":"Balon","sequence":"additional","affiliation":[{"name":"Service de Chirurgie Digestive et G\u00e9n\u00e9rale, H\u00f4pital Claude Huriez\u2014Centre Hospitalier Regional Universitaire, Place de Verdun, 59037 Lille Cedex, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J-P","family":"Triboulet","sequence":"additional","affiliation":[{"name":"Service de Chirurgie Digestive et G\u00e9n\u00e9rale, H\u00f4pital Claude Huriez\u2014Centre Hospitalier Regional Universitaire, Place de Verdun, 59037 Lille Cedex, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2002,11,29]]},"reference":[{"key":"2021070907031885500_bib1","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1002\/(SICI)1097-0142(19981115)83:10<2049::AID-CNCR1>3.0.CO;2-2","article-title":"Changing patterns in the incidence of esophageal and gastric carcinoma in the United States","volume":"83","author":"Devesa","year":"1998","journal-title":"Cancer"},{"key":"2021070907031885500_bib2","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/gut.43.3.327","article-title":"Opposing time trends of peptic ulcer and reflux disease","volume":"43","author":"El-Serag","year":"1998","journal-title":"Gut"},{"key":"2021070907031885500_bib3","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S0011-3840(97)80006-8","article-title":"Gastric cancer","volume":"34","author":"Siewert","year":"1997","journal-title":"Curr Probl Surg"},{"key":"2021070907031885500_bib4","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1002\/bjs.1800650709","article-title":"Adenocarcinoma of the oesophagus and of the oesophagogastric junction","volume":"65","author":"Webb","year":"1978","journal-title":"Br J Surg"},{"key":"2021070907031885500_bib5","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/00000658-200009000-00007","article-title":"Adenocarcinoma of the esophagogastric junction: results of surgical therapy based on anatomical\/topographic classification in 1002 consecutive patients","volume":"232","author":"Siewert","year":"2000","journal-title":"Ann Surg"},{"key":"2021070907031885500_bib6","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1046\/j.1365-2168.1999.01082.x","article-title":"Adenocarcinomas of the distal oesophagus and gastric cardia are one clinical entity. 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