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Mice immune to Listeria monocytogenes fed a liquid diet containing ethanol and challenged with viable bacteria developed steatosis within 24\u2003h and, at a later time, elevated serum alanine aminotransferase levels, indicating more liver damage in this group. Listeria antigen also induced steatosis and increased serum alanine aminotransferase levels in immune ethanol-consuming mice. The production of tumour necrosis factor by a recall immune response in this model is a major, but not the only, component in initiation of alcoholic liver disease.<\/jats:p>","DOI":"10.1046\/j.1365-2249.2001.01529.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T10:27:07Z","timestamp":1047378427000},"page":"123-133","source":"Crossref","is-referenced-by-count":7,"title":["Initiation of alcoholic fatty liver and hepatic inflammation with a specific recall immune response in alcohol-consuming C57Bl\/6 mice"],"prefix":"10.1093","volume":"125","author":[{"given":"I I","family":"Slukvin","sequence":"first","affiliation":[{"name":"Department of Cellular Biology and Anatomy, Louisiana State University Medical Center, Shreveport, LA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P J","family":"Boor","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T R","family":"Jerrells","sequence":"additional","affiliation":[{"name":"Department of Pathology and Microbiology, University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2001,12,20]]},"reference":[{"key":"2022011306425178000_b1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/S0168-8278(87)80003-X","article-title":"Endotoxemia in patients with alcoholic and non-alcoholic cirrhosis and in subjects with no evidence of chronic liver disease following acute alcohol excess","volume":"4","author":"Bode","year":"1987","journal-title":"J Hepatol"},{"key":"2022011306425178000_b2","first-page":"221","article-title":"High interleukin-6 serum levels and increased production by leucocytes in alcoholic liver cirrhosis. 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