{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T20:31:50Z","timestamp":1772915510676,"version":"3.50.1"},"reference-count":6,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2001,12,24]],"date-time":"2001-12-24T00:00:00Z","timestamp":1009152000000},"content-version":"vor","delay-in-days":571,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Endocrinology"],"published-print":{"date-parts":[[2000,6]]},"abstract":"<jats:p>We present a case of Cushing's syndrome where <jats:sup>111<\/jats:sup>In\u2010octreotide scanning provided evidence for the presence of two neuroendocrine tumours. Uptake in the right neck corresponded to a chemodectoma, but there was no change in the clinical condition or fall in ACTH levels following surgical resection. Uptake in the left chest was assumed to relate to a bronchial carcinoid, but a tumour could not initially be localized on magnetic resonance imaging (MRI), spiral CT scanning or on selective venous sampling.<\/jats:p><jats:p>A 1\u2003cm bronchial carcinoid tumour was identified post\u2010mortem which immunostained for ACTH. This case demonstrates that <jats:sup>111<\/jats:sup>ln\u2010octreotide scanning is a useful technique for identifying the source of ectopic ACTH production in difficult cases of Cushing's syndrome. Reliance should not be placed solely on standard imaging techniques to localize the tumour prior to surgery. Although rare, the possibility of a non\u2010ACTH secreting neuroendocrine tumour should also be considered in patients with ectopic ACTH syndrome, who have positive <jats:sup>111<\/jats:sup>In\u2010octreotide scans.<\/jats:p>","DOI":"10.1046\/j.1365-2265.2000.00974.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T10:45:15Z","timestamp":1047379515000},"page":"789-793","source":"Crossref","is-referenced-by-count":8,"title":["Cushing's syndrome associated with a chemodectoma and a carcinoid tumour"],"prefix":"10.1111","volume":"52","author":[{"family":"Tremble","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Buxton\u2010Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Hopkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Kane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Bailey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Harris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,12,24]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(18)30086-0"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03348527"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19801101)46:9<2116::AID-CNCR2820460934>3.0.CO;2-S"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1210\/edrv-12-4-450"},{"key":"e_1_2_4_6_2","first-page":"1147","article-title":"Iodine \u2010123\u2010metaiodobenzylguanidine scintigraphy in patients with chemodectomas of the head and neck region","volume":"31","author":"Van Gils A.P.","year":"1990","journal-title":"Journal of Nuclear Medicine"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1996.134"}],"container-title":["Clinical Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1365-2265.2000.00974.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1365-2265.2000.00974.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1046\/j.1365-2265.2000.00974.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T07:31:30Z","timestamp":1697009490000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1046\/j.1365-2265.2000.00974.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,6]]},"references-count":6,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2000,6]]}},"alternative-id":["10.1046\/j.1365-2265.2000.00974.x"],"URL":"https:\/\/doi.org\/10.1046\/j.1365-2265.2000.00974.x","archive":["Portico"],"relation":{},"ISSN":["0300-0664","1365-2265"],"issn-type":[{"value":"0300-0664","type":"print"},{"value":"1365-2265","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,6]]}}}