{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:08:45Z","timestamp":1787004525095,"version":"build-2736575974"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2002,1,12]],"date-time":"2002-01-12T00:00:00Z","timestamp":1010793600000},"content-version":"vor","delay-in-days":256,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Endocrinology"],"published-print":{"date-parts":[[2001,5]]},"abstract":"<jats:p>\n                    Cardiac phaeochromocytoma is a rare cause of endocrine hypertension. We report a case of a 25\u2010year\u2010old woman, who presented with severe hypertension and intermittent chest pain. The patient denied typical phaeochromocytoma spells of palpitation, headache, and diaphoresis. The 24\u2010hr urinary excretion of norepinephrine was increased sevenfold above the upper limit of normal; however, the excretion of total metanephrines, epinephrine, and dopamine were normal. Computed tomography (CT) scan of the abdomen was normal. An\n                    <jats:sup>131<\/jats:sup>\n                    I\u2010labelled metaiodobenzylguanidine (MIBG) scan was falsely negative while the patient was taking labetalol. The cardiac phaeochromocytoma was localized with indium\u2010111\u2010pentetreotide scintigraphy and chest magnetic resonance imaging scan. Repeat\n                    <jats:sup>123<\/jats:sup>\n                    I\u2010MIBG scintigraphy was positive after discontinuing labetalol. The cardiac phaeochromocytoma was located in the right atrial groove, adjacent to the tricuspid valve, and contained multiple feeder arteries from the right coronary artery. After treatment with volume expansion, \u03b1\u2010methyl\u2010p\u2010tyrosine, and \u03b1\u2010 and \u03b2\u2010adrenergic blockade, surgical resection was performed. While under cardiopulmonary bypass, coronary bypass grafting and tricuspid annuloplasty were performed to facilitate the complete surgical resection of the 4\u00b75\u2010cm tumour. The surgical course was uncomplicated, with complete cure of hypertension and normalization of catecholamine excretion. Post\u2010operative cardiac function, as measured by echocardiogram, was normal. Although cardiac phaeochromocytoma may be highly vascular, invasive and difficult to resect, it can be cured.\n                  <\/jats:p>","DOI":"10.1046\/j.1365-2265.2001.01096.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T05:49:29Z","timestamp":1047361769000},"page":"689-692","source":"Crossref","is-referenced-by-count":17,"title":["Cardiac phaeochromocytoma presenting with severe hypertension and chest pain"],"prefix":"10.1111","volume":"54","author":[{"given":"A. M.","family":"Sawka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"W. F.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. V.","family":"Schaff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,1,12]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"89","article-title":"An atrial pheochromocytoma\u2010induced hypertensive crisis resistant to nitroprusside","volume":"31","author":"Anton A.H.","year":"1993","journal-title":"International Journal of Clinical Pharmacology, Therapy, and Toxicology"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0967-2109(95)94459-a"},{"key":"e_1_2_4_4_1","first-page":"382","article-title":"Experience with heart transplantation for cardiac tumors","volume":"14","author":"Goldstein D.J.","year":"1995","journal-title":"Journal of Heart and Lung Transplantation"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.35.117"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(92)91354-C"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199504000-00013"},{"key":"e_1_2_4_8_1","first-page":"481","article-title":"Labetalol reduces iodine\u2010131 MIBG uptake by pheochromocytoma and normal tissues","volume":"30","author":"Khafagi F.A.","year":"1989","journal-title":"Journal of Nuclear Medicine"},{"key":"e_1_2_4_9_1","unstructured":"Kudva Y.C.&Young W.F.Jr(1997)Sensitivity of 24\u2010hour urine metanephrines and fractionated catecholamines in benign sporadic adrenal pheochromocytoma [abstract #OR28\u20135]. 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