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Indeed, the prototype \u03b3\u03b4 T\u2010cell lymphoma, hepatosplenic T\u2010cell lymphoma constitutes a unique clinicopathological entitity which is intimately associated with a \u03b3\u03b4 T\u2010cell phenotype. However, \u03b3\u03b4 T\u2010cell lymphomas have also been described in other extranodal sites where, unlike reactive \u03b3\u03b4 T\u2010cells and hepatosplenic \u03b3\u03b4 T\u2010cell lymphomas, they display an important morphological heterogeneity. Moreover, these nonhepatosplenic \u03b3\u03b4 T\u2010cell lymphomas are essentially not that different from their \u03b1\u03b2 T\u2010cell receptor for antigen (TCR)\u2010expressing counterparts and thus may be incorporated in the established T\u2010cell lymphoma subclasses. However, subtle differences regarding their histopathological appearance as well as their biological behaviour indicate that further studies to determine the exact significance of TCR expression are required. 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