{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T09:15:00Z","timestamp":1697188500083},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2004,4,7]],"date-time":"2004-04-07T00:00:00Z","timestamp":1081296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Internal Medicine"],"published-print":{"date-parts":[[2004,5]]},"abstract":"<jats:title>Abstract.<\/jats:title><jats:p><jats:bold>Objectives.\u2002<\/jats:bold> Patients with left bundle branch block comprise 5\u20139% of all patients with acute myocardial infarction. Limited data exist on the usefulness of continuous electrocardiographic monitoring of these patients. We have investigated prospectively the usefulness of real\u2010time continuous vectorcardiography for monitoring patients with left bundle branch block and suspicion of acute myocardial infarction.<\/jats:p><jats:p><jats:bold>Design.\u2002<\/jats:bold> A prospective multi\u2010centre study.<\/jats:p><jats:p><jats:bold>Setting.\u2002<\/jats:bold> Fourteen Swedish coronary care units.<\/jats:p><jats:p><jats:bold>Subjects.\u2002<\/jats:bold> Patients with left bundle branch block and suspicion of acute myocardial infarction with &lt;6\u2010h symptom duration were included.<\/jats:p><jats:p><jats:bold>Main outcome measures.\u2002<\/jats:bold> All patients were monitored with continuous vectorcardiography for 12\u201324\u2003h.<\/jats:p><jats:p><jats:bold>Results.\u2002<\/jats:bold> One hundred thirty\u2010three patients were included, 47% had acute myocardial infarction. Patients with acute myocardial infarction showed a marked relative decrease in ST\u2010vector than those without (<jats:italic>P<\/jats:italic>\u2003=\u20030.0002). These changes were most marked in the first 90\u2003min. When comparing patients with acute myocardial infarction receiving thrombolytic therapy or not, those treated with thrombolytics showed more marked decline in ST\u2010vector magnitude (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.0001) and in shorter time (<jats:italic>P<\/jats:italic>\u2003=\u20030.0017). All patients showed STC\u2010vector magnitude changes that were more marked in patients with acute myocardial infarction (<jats:italic>P<\/jats:italic>\u2003=\u20030.0002). An STC\u2010vector magnitude cut\u2010off value of 65\u2003<jats:italic>\u03bc<\/jats:italic>V after 90\u2003min of monitoring gave 54% sensitivity and 72% specificity for diagnosis of acute myocardial infarction.<\/jats:p><jats:p><jats:bold>Conclusion.\u2002<\/jats:bold> Real\u2010time continuous vectorcardiographic monitoring of patients with left bundle branch and suspicion of acute myocardial infarction shows significant differences between those with and without acute myocardial infarction and could be of use for early diagnosis and subsequent monitoring.<\/jats:p>","DOI":"10.1046\/j.1365-2796.2003.01286.x","type":"journal-article","created":{"date-parts":[[2004,12,23]],"date-time":"2004-12-23T23:50:32Z","timestamp":1103845832000},"page":"571-578","source":"Crossref","is-referenced-by-count":2,"title":["Continuous ST\u2010segment monitoring of patients with left bundle branch block and suspicion of acute myocardial infarction"],"prefix":"10.1111","volume":"255","author":[{"given":"G.","family":"Gunnarsson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Eriksson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Dellborg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,4,7]]},"reference":[{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.46.4.753"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.10.2424"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-129-9-199811010-00003"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.58.4.679"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00446-4"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)91161-4"},{"key":"e_1_2_11_8_2","unstructured":"RyanTJAE BrooksNH CaliffRMet al.ACC\/AHA guidelines for the management of patients with acute myocardial infarction: 1999 update: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). 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