{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T12:44:24Z","timestamp":1765975464604},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2001,12,25]],"date-time":"2001-12-25T00:00:00Z","timestamp":1009238400000},"content-version":"vor","delay-in-days":724,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:p>Vitamin A deficiency even at subclinical levels is associated with increased childhood mortality. There have been few studies related to vitamin A status of children in Turkey. The aim of this study was to assess vitamin A status of children aged 6\u201359 months in \u0130zmir, Turkey, and to evaluate the relationship of these levels with nutritional status. One hundred and sixty children were selected for the study using the cluster sampling method. Serum retinol levels were measured by high\u2010performance liquid chromatography (HPLC) and ranged from 9.8 to 59.2 \u03bcg\/dL (mean 29.3\u2003\u00b1\u20039.5 \u03bcg\/dL). Levels were below the lower limit of the normal range in 15.6% of the children. Deficient and marginal serum retinol among stunted children were observed in 16% and 42% respectively. There was a statistically significant relationship between low serum retinol and stunting (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.05). Although xerophthalmia and other clinical signs of vitamin A deficiency are rarely seen, subclinical vitamin A deficiency is a public health problem in \u0130zmir, Turkey.<\/jats:p>","DOI":"10.1046\/j.1365-3016.2000.00229.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T17:43:06Z","timestamp":1047490986000},"page":"64-69","source":"Crossref","is-referenced-by-count":19,"title":["Vitamin A deficiency in healthy children aged 6\u201359 months in \u0130zmir Province of Turkey"],"prefix":"10.1111","volume":"14","author":[{"family":"Kurug\u00f6l","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Egemen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Keskinog\u02c7lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Darcan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Ak\u015fit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,12,25]]},"reference":[{"key":"e_1_2_6_2_2","unstructured":"BarnessLA&CurranJS.Vitamin deficiencies and excesses.In:Nelson Textbook of Pediatrics.Editors: Behrman RE Kliegman RM Arvin AM. Philadelphia: WB Saunders Company 1996; pp.172185."},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)90677-3"},{"key":"e_1_2_6_4_2","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1093\/ajcn\/46.5.827","article-title":"Mild vitamin A deficiency and childhood morbidity: an Indian experience.","volume":"46","author":"Milton R","year":"1987","journal-title":"American Journal of Clinical Nutrition"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)91879-Q"},{"key":"e_1_2_6_6_2","unstructured":"World Health Organisation.Control of vitamin A deficiency xerophthalmia. Report of a Joint WHO\/UNICEF\/USAID\/Helen Keller International IVAGC Meeting.WHO Technical Report Series 1982; report no. 672."},{"key":"e_1_2_6_7_2","unstructured":"EastmanSJ.Vitamin A: Deficiency and Xerophthalmia.UNICEF Press 1988."},{"key":"e_1_2_6_8_2","unstructured":"Czajka\u2010NarinsDMVitamins.In:Krause\u2019s Food Nutrition Diet Therapy.Editors: Mahan LK Stump\u2010Escott S. Philadelphia: WB Saunders Company 1996; pp.77122."},{"key":"e_1_2_6_9_2","first-page":"159","article-title":"Serum vitamin A and carotene levels in children with PEM.","volume":"22","author":"Hasanog\u02c7lu A","year":"1979","journal-title":"\u00c7ocuk Sag\u02c7l\u0131g\u02c7\u0131ve Hastal\u0131klar\u0131 Dergisi"},{"key":"e_1_2_6_10_2","first-page":"65","article-title":"Eye findings and serum vitamin A levels in children with malnutrition from Sivas.","volume":"10","author":"Tanzer F","year":"1986","journal-title":"Dog\u02c7a"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/36.5.251"},{"key":"e_1_2_6_12_2","first-page":"193","article-title":"Vitamin A levels of children with measles in Ankara, Turkey.","volume":"37","author":"Hatun \u015e","year":"1995","journal-title":"Turkish Journal of Pediatrics"},{"key":"e_1_2_6_13_2","first-page":"187","article-title":"Vitamin A status of healthy infants in Ankara, Turkey.","volume":"37","author":"Hatun \u015e","year":"1995","journal-title":"Turkish Journal of Pediatrics"},{"key":"e_1_2_6_14_2","unstructured":"A\u00e7kurtF WetheriltH OkanB BrubacherG Akta\u015fS T\u00fcrd\u00fcS.T\u00fcrkiyenin \u00dc\u00e7 B\u00f6lgesinde 7\u201317 Ya\u015f Grubu Okul \u00c7ocuklarinin B\u00fcy\u00fcme\u2010Geli\u015fme Vitamin Ve Mineraller Y\u00f6n\u00fcnden Beslenme Durumlar\u0131n\u0131n Saptanmas\u0131. T\u00dcBITAK yayinlari: \u0130TAK Press 1989; pp.183"},{"key":"e_1_2_6_15_2","unstructured":"OlsonJA.Vitamin A.In:Handbook of Vitamins.Editor: Lawrence JM. New York: Marcell Dekker Inc. 1991; pp.157."},{"key":"e_1_2_6_16_2","unstructured":"Nutritive Values of the Edible Part of Food(Appendix 41 fromNutritive Value of Foods. Home and Garden Bulletin no. 72. US Department of Agriculture. Washington DC: US Government Printing Office 1988). In:Krause\u2019s Food Nutrition and Diet Therapy. Editors: Mahan LK Stump\u2010Escott S. Philadelphia: WB Saunders Company 1996; pp.10161091."},{"key":"e_1_2_6_17_2","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1016\/S0002-8223(21)02462-7","article-title":"The 10th edition of the Recommended Dietary Allowances: what\u2019s new in the 1989 RDAs?","volume":"89","author":"Monsen ER.","year":"1989","journal-title":"Journal of the American Dietetic Association"},{"key":"e_1_2_6_18_2","first-page":"929","article-title":"Use and interpretation of anthropometric indicators of nutritional status.","volume":"64","author":"WHO Working Group.","year":"1986","journal-title":"Bulletin of the World Health Organisation"},{"key":"e_1_2_6_19_2","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1093\/ajcn\/58.1.91","article-title":"Undernutrition and vitamin A deficiency in the Department of Lingu\u00e8re, Louga region of S\u00e9n\u00e9gal.","volume":"58","author":"Rankins J","year":"1993","journal-title":"American Journal of Clinical Nutrition"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)82545-4"},{"key":"e_1_2_6_21_2","unstructured":"World Health Organization.Vitamin A deficiency and xerophthalmia.WHO Technical Report Series 1976; report no. 590."},{"key":"e_1_2_6_22_2","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1093\/ajcn\/40.6.1281","article-title":"Assessment of marginal vitamin A deficiency in Brazilian children using the relative dose response procedure.","volume":"40","author":"Flores H","year":"1984","journal-title":"American Journal of Clinical Nutrition"},{"key":"e_1_2_6_23_2","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1093\/ajcn\/52.6.1064","article-title":"The modified relative dose response assay as an indicator of vitamin A status in a population of well\u2010nourished American children.","volume":"52","author":"Tanumihardjo SA","year":"1990","journal-title":"American Journal of Clinical Nutrition"},{"key":"e_1_2_6_24_2","first-page":"456","article-title":"Vitamin A deficiency and protein\u2013energy malnutrition in a sample of pre\u2010school age children in the Kivu Province in Zaire.","volume":"50","author":"Donnen P","year":"1996","journal-title":"European Journal of Clinical Nutrition"},{"key":"e_1_2_6_25_2","unstructured":"EgemenA.Organizmada vitamin A gereksinimini art\u0131ran durumlar.In:Vitaminlerin Sag\u02c7l\u0131g\u02c7\u0131m\u0131zdaki \u00d6nemi.Editor: Egemen A. Istanbul: Roche yayinlari pp.933."},{"key":"e_1_2_6_26_2","unstructured":"Republic of Turkey Ministry of Health.Country Health Report 1997.Ankara: Republic of Turkey Ministry of Health 1997."},{"key":"e_1_2_6_27_2","unstructured":"Ministry of Health (Turkey) Hacettepe University Institute of Population Studies and Macro International Inc.Turkey Demographic and Health Survey 1993.Ankara: Ministry of Health (Turkey) 1994."}],"container-title":["Paediatric and Perinatal Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1365-3016.2000.00229.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1046\/j.1365-3016.2000.00229.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T12:04:06Z","timestamp":1698581046000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1046\/j.1365-3016.2000.00229.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,1]]}},"alternative-id":["10.1046\/j.1365-3016.2000.00229.x"],"URL":"https:\/\/doi.org\/10.1046\/j.1365-3016.2000.00229.x","archive":["Portico"],"relation":{},"ISSN":["0269-5022","1365-3016"],"issn-type":[{"value":"0269-5022","type":"print"},{"value":"1365-3016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,1]]}}}