{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:00:52Z","timestamp":1791302452411,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2002,11,8]],"date-time":"2002-11-08T00:00:00Z","timestamp":1036713600000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Veterinary Medicine Series A"],"published-print":{"date-parts":[[2002,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Adult female beef cattle found positive for stanozolol in the urine were investigated for liver pathology. In all the animals toxic hepatitis was found, including cholestasis, periportal fibrosis and inflammation, focal necrosis and blood filled lacunae. As no clinical data of the cows were available, apart from the history of illegal stanozolol abuse, it is not possible to attribute all changes to the illegal hormone treatment. Moreover, the cows have probably been treated with a cocktail, and apart from stanozolol more anabolic steroids may have been used. Management factors, viral and bacterial infections, former caesarean sections and especially feeding regime may also be responsible for the lesions described. Striking similarities with data from hepatotoxicity found in human body builders using similar agents, however, suggest a major role of stanozolol as causative agent.<\/jats:p>","DOI":"10.1046\/j.1439-0442.2002.00477.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T09:12:13Z","timestamp":1047460333000},"page":"466-469","source":"Crossref","is-referenced-by-count":6,"title":["Hepatitis in Growth Promoter Treated Cows"],"prefix":"10.1111","volume":"49","author":[{"given":"M. J.","family":"Groot","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,11,8]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4547(19970115)47:2<186::AID-JNR7>3.0.CO;2-B"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0232-1513(88)80092-6"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5919(05)70175-7"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002040050636"},{"key":"e_1_2_5_6_1","volume-title":"Endocrinology","author":"Catlin D.","year":"1995"},{"key":"e_1_2_5_7_1","first-page":"113","article-title":"Drug\u2010induced cholestasis","volume":"12","author":"Chitturi S.","year":"2001","journal-title":"Semin. Gastrointest. Dis."},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.41.4.441"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-199309060-00007"},{"key":"e_1_2_5_10_1","first-page":"2584","article-title":"Sex hormones and hepatic neoplasia","volume":"36","author":"Goldfarb S.","year":"1976","journal-title":"Cancer Res."},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-199005060-00007"},{"key":"e_1_2_5_12_1","first-page":"399","article-title":"Androgenic anabolic steroid\u2010induced intrahepatic cholestasis: a review with four additional case reports","volume":"87","author":"Gurakar A.","year":"1994","journal-title":"J. Okla State Med. Assoc."},{"key":"e_1_2_5_13_1","first-page":"2351","volume-title":"Endocrinology","author":"Handelsman D. J.","year":"1995"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2000.217.681"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0300-483X(77)90053-1"},{"key":"e_1_2_5_16_1","first-page":"74","volume-title":"Carcinogenic Hormones","author":"Ishak K. G.","year":"1979"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(72)92649-9"},{"key":"e_1_2_5_18_1","volume-title":"Pathology of Domestic Animals","author":"Jubb K. V. F.","year":"1993"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5919(05)70031-4"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4731(86)90099-3"},{"key":"e_1_2_5_21_1","first-page":"405","article-title":"Peliosis hepatis, twelve cases associated with oral androgen therapy","volume":"101","author":"Nadell J.","year":"1977","journal-title":"Arch. Pathol. Lab. Med."},{"key":"e_1_2_5_22_1","first-page":"208","article-title":"Phlebectatic peliosis hepatis in Australian cattle","volume":"26","author":"Seawright A. A.","year":"1984","journal-title":"Vet. Hum. Tox."},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(87)80277-4"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0676.1992.tb00560.x"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1034591"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.2000.02091.x"},{"key":"e_1_2_5_27_1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1093\/ptj\/75.5.426","article-title":"Ergogenic aids","volume":"75","author":"Thein L.","year":"1995","journal-title":"Phys. Ther."},{"key":"e_1_2_5_28_1","first-page":"332","article-title":"Hepatic lesions in patients on anabolic androgen therapy","volume":"19","author":"Turani H.","year":"1983","journal-title":"Isr. J. Med. Sci."},{"key":"e_1_2_5_29_1","first-page":"1079","article-title":"High incidence of peliosis hepatis in autopsy cases of aplastic anemia with special reference to anabolic steroid therapy","volume":"34","author":"Wakabayashi T.","year":"1984","journal-title":"Acta Pathol. Jpn."},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/1056-8719(94)00073-D"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-1981(00)00183-9"},{"key":"e_1_2_5_32_1","first-page":"791","article-title":"At what price, glory? Severe cholestasis and acute renal failure in an athlete abusing stanozolol","volume":"151","author":"Yosida E. M.","year":"1994","journal-title":"Can. Med. Assoc. J."}],"container-title":["Journal of Veterinary Medicine Series A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1439-0442.2002.00477.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1046\/j.1439-0442.2002.00477.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T18:48:43Z","timestamp":1697222923000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1046\/j.1439-0442.2002.00477.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,11]]},"references-count":31,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2002,11]]}},"alternative-id":["10.1046\/j.1439-0442.2002.00477.x"],"URL":"https:\/\/doi.org\/10.1046\/j.1439-0442.2002.00477.x","archive":["Portico"],"relation":{},"ISSN":["0931-184X"],"issn-type":[{"value":"0931-184X","type":"print"}],"subject":[],"published":{"date-parts":[[2002,11]]}}}