{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T19:35:28Z","timestamp":1791142528341,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"7-8","license":[{"start":{"date-parts":[[2002,10,17]],"date-time":"2002-10-17T00:00:00Z","timestamp":1034812800000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2002,10]]},"abstract":"<jats:p><jats:bold>Summary.\u2003<\/jats:bold>Ozonized sunflower oil, Oleozon<jats:sup>\u00ae<\/jats:sup>, has a remarkable germicidal action. In the present study, the efficacy of Oleozon<jats:sup>\u00ae<\/jats:sup>in the treatment of tinea pedis was demonstrated in a controlled randomized phase III assay, comparing topical Oleozon<jats:sup>\u00ae<\/jats:sup>with ketoconazole cream 2% (Nizoral<jats:sup>\u00ae<\/jats:sup>) in 200 patients (100 in each group). The treatment administered was twice per day for a period of 6\u2003weeks. The efficacy was evaluated clinically (disappearance of all lesions, with or without negative mycological results) and mycologically (negative culture results). A complete clinical and mycological cure was obtained in 75 and 81% for Oleozon<jats:sup>\u00ae<\/jats:sup>and ketoconazole, respectively, with no significant differences between both groups. No side\u2010effects or bacterial super\u2010infections were observed. Patients were evaluated 6\u2003months after the end of the treatment and no recurrence was observed in the Oleozon<jats:sup>\u00ae<\/jats:sup>group. Oleozon<jats:sup>\u00ae<\/jats:sup>can be an effective alternative low\u2010cost antimycotic drug.<\/jats:p>","DOI":"10.1046\/j.1439-0507.2002.00780.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T14:49:31Z","timestamp":1047480571000},"page":"329-332","source":"Crossref","is-referenced-by-count":40,"title":["Efficacy of ozonized sunflower oil in the treatment of tinea pedis"],"prefix":"10.1111","volume":"45","author":[{"given":"S.","family":"Men\u00e9ndez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Falc\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. 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