{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T23:32:39Z","timestamp":1783553559572,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2001,12,21]],"date-time":"2001-12-21T00:00:00Z","timestamp":1008892800000},"content-version":"vor","delay-in-days":234,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2001,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background and Aims:<\/jats:bold> The purpose of this study was to investigate the relationship between gastric metaplasia and <jats:italic>Helicobacter pylori<\/jats:italic> in patients with endoscopic duodenitis.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> The subjects were 57 patients with endoscopic duodentitis with or without <jats:italic>H. pylori\u2010<\/jats:italic>associated gastritis. Biopsy specimens were obtained from the stomach and duodenal bulb to assess the histological findings and <jats:italic>H. pylori<\/jats:italic> infection. Gastric metaplasia was divided into three types: complete, intermediate and incomplete, according to the amount of mucus in the metaplastic cells. In 10 <jats:italic>H. pylori<\/jats:italic>\u2010positive patients, endoscopic and histological findings of duodenitis were compared before and after eradication of the bacteria.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> There was no significant difference in the extent of gastric metaplasia or the appearance and severity of endoscopic duodenitis between <jats:italic>H. pylori<\/jats:italic>\u2010positive and \u2010negative groups. The complete type of gastric metaplasia was frequently detected in the <jats:italic>H. pylori<\/jats:italic>\u2010negative group, whereas the incomplete type was frequently observed in the <jats:italic>H. pylori<\/jats:italic>\u2010positive group. After eradication of <jats:italic>H. pylori<\/jats:italic>, the incomplete type changed to the complete type with a decrease of histological inflammation.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> The complete type of gastric metaplasia occurred frequently without <jats:italic>H. pylori<\/jats:italic> infection, whereas the incomplete type was frequently associated with <jats:italic>H. pylori<\/jats:italic> infection.<\/jats:p>","DOI":"10.1046\/j.1440-1746.2001.02482.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T05:19:31Z","timestamp":1047446371000},"page":"513-518","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Endoscopic duodenitis, gastric metaplasia and <i>Helicobacter pylori<\/i>"],"prefix":"10.1111","volume":"16","author":[{"given":"Yoshihito","family":"Urakami","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"Sano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2001,12,21]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.3.5877.430"},{"key":"e_1_2_5_3_2","first-page":"177","article-title":"Duodenitis.","volume":"61","author":"Gregg JA","year":"1974","journal-title":"Am. J. Gastroenterol."},{"key":"e_1_2_5_4_2","first-page":"213","article-title":"Changing concepts of duodenitis.","volume":"64","author":"Gelzayd EA","year":"1975","journal-title":"Am. J. Gastroenterol."},{"key":"e_1_2_5_5_2","volume-title":"Duodenitis","author":"Cheli R","year":"1976"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365528509103941"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.1991.tb01469.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0145-2134(96)00067-1"},{"key":"e_1_2_5_9_2","first-page":"221","article-title":"Gastric metaplasia of surface epithelium in the duodenal mucosa.","volume":"72","author":"Urakami Y.","year":"1975","journal-title":"Nippon Shokakibyo Gakkai Zasshi"},{"key":"e_1_2_5_10_2","first-page":"795","article-title":"Gastric metaplasia and Helicobacter pylori.","volume":"92","author":"Urakami Y","year":"1997","journal-title":"Am. J. Gastroenterol."},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.43.12.981"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1996.v110.pm8566592"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.34.11.1510"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700400203"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365528909091303"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.5.4.285"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.39.4.513"}],"container-title":["Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1440-1746.2001.02482.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1046\/j.1440-1746.2001.02482.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T00:23:22Z","timestamp":1697675002000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1046\/j.1440-1746.2001.02482.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,5]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,5]]}},"alternative-id":["10.1046\/j.1440-1746.2001.02482.x"],"URL":"https:\/\/doi.org\/10.1046\/j.1440-1746.2001.02482.x","archive":["Portico"],"relation":{},"ISSN":["0815-9319","1440-1746"],"issn-type":[{"value":"0815-9319","type":"print"},{"value":"1440-1746","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,5]]},"assertion":[{"value":"2001-12-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}