{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T10:47:14Z","timestamp":1761216434296},"reference-count":27,"publisher":"Wiley","issue":"s1","license":[{"start":{"date-parts":[[2002,1,4]],"date-time":"2002-01-04T00:00:00Z","timestamp":1010102400000},"content-version":"vor","delay-in-days":490,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropathology"],"published-print":{"date-parts":[[2000,9]]},"abstract":"<jats:p>It is valuable to summarize the milestone study of prion diseases done in Japan for review in the journal <jats:italic>Neuropathology<\/jats:italic> in 2000. Many studies done in Japan promote world prion research activity, and also influence further research projects in other groups abroad. 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