{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T07:38:19Z","timestamp":1777534699367,"version":"3.51.4"},"reference-count":49,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2003,8,28]],"date-time":"2003-08-28T00:00:00Z","timestamp":1062028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Major depression is a multifactorial disorder. Previous studies have mainly evaluated work stress to determine the risk factors for depression among workers. The present study aimed to determine factors predictive of the first depressive episode 1\u2003year later among white\u2010collar workers, and to examine whether work \u2018stress\u2019 is associated with an elevated risk of depression. A 5\u2003year open\u2010cohort study was carried out in a Japanese company. The odds ratios (OR) of the development of depression 1\u2003year later were calculated. Ninety\u2010eight first\u2010onset cases were compared with 1267 never\u2010ill cases. Forward stepwise multiple logistic regression indicated that the first onset of depression was associated with a past history of panic attack (OR: 5.14; 95% confidence interval (CI): 1.64\u201316.10), neuroticism (OR: 3.59; 95%CI: 2.06\u20136.26), perceived overprotection (OR: 2.75; 95%CI: 1.66\u20134.55), poor support (OR: 2.55; 95%CI: 1.58\u20134.10), and low care (OR: 2.23; 95%CI: 1.23\u20134.04). First\u2010onset cases were more likely to have had objective work events (OR: 1.50; 95%CI: 1.18\u20131.90) but they did not differ from never\u2010ill cases in subjective job stress. The development of major depression in white\u2010collar workers is associated with multiple factors, as is depression in the community.<\/jats:p>","DOI":"10.1046\/j.1440-1819.2003.01158.x","type":"journal-article","created":{"date-parts":[[2003,8,28]],"date-time":"2003-08-28T10:08:24Z","timestamp":1062065304000},"page":"523-531","source":"Crossref","is-referenced-by-count":35,"title":["Predictors of first\u2010onset major depressive episodes among white\u2010collar workers"],"prefix":"10.1111","volume":"57","author":[{"given":"Madoka","family":"Tokuyama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhisa","family":"Nakao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masako","family":"Seto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatoshi","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,8,28]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"3","article-title":"A research framework for evaluating the promotion of mental health and prevention of mental illness","volume":"96","author":"Eisenberg L","year":"1981","journal-title":"Public Health Rep."},{"key":"e_1_2_5_3_2","first-page":"983","article-title":"The economic impact of depression in a workplace","volume":"36","author":"Conti DJ","year":"1994","journal-title":"J. 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