{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T18:23:58Z","timestamp":1785867838204,"version":"3.56.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2002,2,26]],"date-time":"2002-02-26T00:00:00Z","timestamp":1014681600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asia Pac J Clin Nutr"],"published-print":{"date-parts":[[2002,3]]},"abstract":"<jats:p>To investigate the efficacy of two different iron supplements administered either on a weekly basis or during menstruation, a 16\u2010week community experimental study was carried out among postmenarcheal female adolescent students in Kupang, East Nusa Tenggara, Indonesia. Forty eight students received a placebo tablet weekly, 48 other students got an iron tablet weekly and 41 students took an iron tablet for four consecutive days during their menstruation cycle. All subjects were given deworming tablets before supplementation. Haemoglobin, serum ferritin, height, weight, mid\u2010upper arm circumference and dietary intake were assessed before and after intervention. The supplementation contributed to a significant improvement in the iron status of the intervention groups compared to the placebo group (<jats:italic>P<\/jats:italic> &lt; 0.05). In the menstruation group, the haemoglobin concentrations of the anaemic subjects improved significantly (<jats:italic>P<\/jats:italic> &lt; 0.05) while for the non\u2010anaemic subjects, serum ferritin concentrations also increased significantly (<jats:italic>P<\/jats:italic> &lt; 0.05). In the weekly group for anaemic and non\u2010anaemic subjects, there was a significant increase in both haemoglobin and serum ferritin concentrations (<jats:italic>P<\/jats:italic> &lt; 0.05). This study revealed that weekly supplementation of iron tablets continued for 16 weeks contributed a higher improvement to haemoglobin concentration, compared with supplementing iron tablets for four consecutive days during menstruation for four menstrual cycles. This suggests that weekly iron supplementation is preferable.<\/jats:p>","DOI":"10.1046\/j.1440-6047.2002.00264.x","type":"journal-article","created":{"date-parts":[[2003,3,10]],"date-time":"2003-03-10T11:23:22Z","timestamp":1047295402000},"page":"36-41","source":"Crossref","is-referenced-by-count":15,"title":["Will iron supplementation given during menstruation improve iron status better than weekly supplementation?"],"prefix":"10.1111","volume":"11","author":[{"given":"Judhiastuty","family":"Februhartanty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Drupadi","family":"Dillon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helda","family":"Khusun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,2,26]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/124.suppl_8.1479S"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1079\/NRR19960015"},{"key":"e_1_2_6_4_2","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1177\/156482659601700105","article-title":"Iron\u2010supplementation programmes. 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Improving Iron and Zinc Nutrition in Infancy and Early Childhood Proceedings of the Bali Consultation Meeting for the planning of multi\u2010country iron and zinc intervention trials. Bali: UNICEF 1997."},{"key":"e_1_2_6_8_2","unstructured":"DallmanPR.Changing iron needs from birth through adolescence. In: Fomon SJ Zlotkin S eds. Nutritional Anemia. Nestl\u00e9 Nutrition Workshop Series Vol. 30. New York: Nestec 1992."},{"key":"e_1_2_6_9_2","unstructured":"Fairweather\u2010TaitS.Iron Biochemistry. In: British Nutrition Foundation. Iron Nutritional Physiological Significance. London: Chapman and Hall 1995."},{"key":"e_1_2_6_10_2","unstructured":"AggettP.Iron and Women in Reproductive Years. In: British Nutrition Foundation. Iron Nutritional Physiological Significance. London: Chapman and Hall 1995."},{"key":"e_1_2_6_11_2","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1093\/ajcn\/54.6.1047","article-title":"Iron requirements in menstruating women.","volume":"54","author":"Hallberg L","year":"1991","journal-title":"Am J Clin Nutr"},{"key":"e_1_2_6_12_2","first-page":"200","article-title":"Iron balance in menstruating women","volume":"49","author":"Hallberg L","year":"1995","journal-title":"Eur J Clin Nutr"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/61.1.111"},{"key":"e_1_2_6_14_2","first-page":"181","article-title":"The effects of weekly iron supplementation with folic acid, vitamin A, vitamin C on iron status of Indonesian adolescents.","volume":"5","author":"Katelhut A","year":"1996","journal-title":"Asia Pac J Clin Nutr"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)92378-7"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/63.6.884"},{"key":"e_1_2_6_17_2","unstructured":"HassardTH.Understanding Biostatistics. London: Mosby Year Book 1991."},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/66.1.177"},{"key":"e_1_2_6_19_2","unstructured":"WHO. Physical status. The use and interpretation of anthropometry. Report of WHO expert committee. Geneva: WHO 1995."},{"key":"e_1_2_6_20_2","unstructured":"INACG. Measurement of Iron Status. A report of the International Nutritional Anemia Consultative Group (INACG). Washington DC USA: The Nutrition Foundation 1985."},{"key":"e_1_2_6_21_2","unstructured":"NguyenTL.Effects of vitamin A and iron fortified supplementary food on vitamin A and iron status of rural preschool children in Vietnam (PhD Thesis). SEAMEO\u2010TROPMED RCCN University of Indonesia Jakarta Indonesia 1997."},{"key":"e_1_2_6_22_2","unstructured":"Ministry of Health.The protocols of iron supplement administration for community workers. Republic of Indonesia: Directorate of Community Nutrition Directorate General of Community Health Ministry of Health 1996."},{"key":"e_1_2_6_23_2","unstructured":"BothwellTH CharltonRW.Iron deficiency in women. A report of the International Nutritional Anemia Consultative Group (INACG). Washington DC USA: The Nutrition Foundation 1981."},{"key":"e_1_2_6_24_2","unstructured":"LanzkowskyP.Iron Deficiency in Adolescents. In: Winick M ed. Adolescent Nutrition. New York: John Wiley and Sons 1982."},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/127.1.177"},{"key":"e_1_2_6_26_2","first-page":"82","article-title":"True absorption and retention of supplemental iron is more efficient when iron is administered every three days rather than daily to iron\u2010normal and iron\u2010deficient rats.","volume":"125","author":"Viteri FE","year":"1995","journal-title":"J Nutr"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/51.4.649"},{"key":"e_1_2_6_28_2","unstructured":"Fairweather\u2010TaitS.Iron Absorption. In: British Nutrition Foundation. Iron Nutritional Physiological Significance. 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