{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:32:10Z","timestamp":1791203530721,"version":"4.2.0"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,10,9]],"date-time":"2008-10-09T00:00:00Z","timestamp":1223510400000},"content-version":"vor","delay-in-days":3204,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J of Neuroscience"],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The paravermal cerebellar cortex contains three spatially separate zones (the C1, C3 and Y zones) which form a functionally coupled system involved in the control of voluntary limb movements. A series of \u2018modules\u2019 has been postulated, each defined by a set of olivary neurons with similar receptive fields, the cortical microzones innervated by these neurons and the group of deep cerebellar nuclear neurons upon which the microzones converge. A key feature of this modular organization is a correspondence between cortical input and output, irrespective of the zonal identity of the microzone. This was tested directly using a combined electrophysiological and bi\u2010directional tracer technique in barbiturate\u2010anaesthetized cats. During an initial operation, small injections of a mix of retrograde and anterograde tracer material (red beads combined with Fluoro\u2010Ruby or green beads combined with biotinylated dextran amine or Fluoro\u2010Emerald) were made into areas of the medial C1 and medial C3 zones in cerebellar lobule V characterized by olivo\u2010cerebellar input from the ventral forelimb. The inferior olive and the deep cerebellar nuclei were then scrutinized for retrogradely labelled cells and anterogradely labelled axon terminals, respectively. For individual experiments, the degree of C1\u2013C3 zone terminal field overlap in the nucleus interpositus anterior was plotted as a function of either the regional overlap of single\u2010labelled cells or the proportion of double\u2010labelled cells in the dorsal accessory olive. The results were highly positively correlated, indicating that cortico\u2010nuclear convergence between parts of the two zones is in close proportion to the corresponding olivo\u2010cerebellar divergence, entirely consistent with the modular hypothesis.<\/jats:p>","DOI":"10.1046\/j.1460-9568.2000.00897.x","type":"journal-article","created":{"date-parts":[[2003,3,6]],"date-time":"2003-03-06T09:26:37Z","timestamp":1046942797000},"page":"205-214","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Precise matching of olivo\u2010cortical divergence and cortico\u2010nuclear convergence between somatotopically corresponding areas in the medial C1 and medial C3 zones of the paravermal cerebellum"],"prefix":"10.1111","volume":"12","author":[{"given":"R.","family":"Apps","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Garwicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,10,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00239553"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19981005)399:4<513::AID-CNE5>3.0.CO;2-4"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.1999.0875u.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00228515"},{"key":"e_1_2_7_6_1","first-page":"183","article-title":"Topographical localisation in the projections from the inferior olive to the paravermal cortex of the anterior lobe and paramedian lobule in the cerebellum of the cat. 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