{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:11:51Z","timestamp":1790802711497,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2001,12,24]],"date-time":"2001-12-24T00:00:00Z","timestamp":1009152000000},"content-version":"vor","delay-in-days":723,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetic Medicine"],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:bold>Aims<\/jats:bold>To establish the incidence of post\u2010transplant diabetes mellitus (PTDM) and factors predictive of its development.<\/jats:p><jats:p><jats:bold>Methods<\/jats:bold>This was a retrospective review (using hospital records and transplant database) of 97 consecutive adult patients who underwent cardiac transplantation at St Vincent\u2019s Hospital, Sydney, Australia.<\/jats:p><jats:p><jats:bold>Results<\/jats:bold>Mean follow\u2010up was 27\u2003months. Excluding five patients who had pre\u2010existing diabetes, the cumulative incidence of PTDM was 15.7%. Pre\u2010transplant random blood glucose (5.6\u2003\u00b1\u20030.8 vs. 5.2\u2003\u00b1\u20030.6\u2003mmol\/l,<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.05), family history (46% vs. 15%,<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.05) and a continuing requirement for insulin on the second post\u2010transplant day (54% vs. 15%,<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.01) differed in those who developed PTDM as opposed to those who remained free of diabetes. Patients who developed PTDM had received slightly higher mean doses of prednisolone at three months (0.21\u2003\u00b1\u20030.03 vs. 0.19\u2003\u00b1\u20030.03\u2003mg. kg<jats:sup>\u22121.<\/jats:sup>day<jats:sup>\u22121<\/jats:sup>,<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.01). Of the factors identifiable prior to initial hospital discharge, only family history of diabetes mellitus and second post\u2010transplant day insulin requirement independently predicted the occurrence of PTDM.<\/jats:p><jats:p><jats:bold>Conclusions<\/jats:bold>A family history of diabetes and the need for insulin beyond the first 24\u2003h after transplantation are factors identifiable prior to hospital discharge, which predict patients at risk of developing PTDM. In such patients, consideration to minimizing the dose of glucocorticoids should be given where possible.<\/jats:p>","DOI":"10.1046\/j.1464-5491.2000.00206.x","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T09:49:57Z","timestamp":1027676997000},"page":"15-19","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":81,"title":["Predicting the occurrence of diabetes mellitus in recipients of heart transplants"],"prefix":"10.1111","volume":"17","author":[{"given":"B.","family":"Depczynski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Daly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. V.","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. 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