{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T13:05:07Z","timestamp":1789909507129,"version":"4.0.1"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2002,3,14]],"date-time":"2002-03-14T00:00:00Z","timestamp":1016064000000},"content-version":"vor","delay-in-days":72,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives<\/jats:bold> To determine the safety and efficacy of imiquimod (Aldara\u2122) 5% cream in the treatment of prepuce\u2010associated warts in uncircumcised males.<\/jats:p><jats:p><jats:bold>Methods<\/jats:bold> An open\u2010label study in six UK medical centres with 35 uncircumcised males with prepuce\u2010associated warts treated with imiquimod 5% cream three times per week for up to 16\u00a0weeks. Other anogenital warts were also treated.<\/jats:p><jats:p><jats:bold>Results<\/jats:bold> Three times weekly application of imiquimod was found to be safe, with erythema as the most commonly reported local skin reaction. Forty per cent of patients had complete clearance of anogenital warts within 16\u00a0weeks.<\/jats:p><jats:p><jats:bold>Conclusions<\/jats:bold> Imiquimod cream at a dosing regimen of three times per week, is effective and has an acceptable safety profile in the treatment of prepuce associated warts and other external anogenital warts in uncircumcised males.<\/jats:p>","DOI":"10.1046\/j.1468-3083.2002.00366.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T04:41:59Z","timestamp":1047444119000},"page":"58-62","source":"Crossref","is-referenced-by-count":9,"title":["Imiquimod 5% cream is an acceptable treatment option for external anogenital warts in uncircumcised males"],"prefix":"10.1111","volume":"16","author":[{"given":"RD","family":"Maw","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GR","family":"Kinghorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CA","family":"Bowman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BT","family":"Goh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AT","family":"Nayagam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Nathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,3,14]]},"reference":[{"issue":"4","key":"e_1_2_6_2_2","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1097\/00007435-199904001-00002","article-title":"Estimates of the incidence and prevalence of sexually transmitted diseases in the United States. 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