{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T03:55:19Z","timestamp":1768276519201,"version":"3.49.0"},"reference-count":7,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2002,3,14]],"date-time":"2002-03-14T00:00:00Z","timestamp":1016064000000},"content-version":"vor","delay-in-days":72,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background<\/jats:bold> The exact aetiology of recurrent aphthous stomatitis (RAS) is still unknown, but different predisposing factors, including iron, vitamin B12 and folic acid deficiencies, have been proposed.<\/jats:p><jats:p><jats:bold>Material and methods<\/jats:bold> Serum iron, ferritin, folic acid and vitamin B12 levels were investigated in 35 patients with RAS and in 26 healthy controls.<\/jats:p><jats:p><jats:bold>Results<\/jats:bold> Vitamin B12 levels were found significantly lower in subjects with RAS than in controls. No significant differences were found in other parameters.<\/jats:p><jats:p><jats:bold>Conclusion<\/jats:bold> We concluded that vitamin B12 deficiency may be an aetiological factor in recurrent aphthous stomatitis.<\/jats:p>","DOI":"10.1046\/j.1468-3083.2002.00369.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T04:41:59Z","timestamp":1047444119000},"page":"66-67","source":"Crossref","is-referenced-by-count":82,"title":["Serum iron, ferritin, folic acid, and vitamin B12 levels in recurrent aphthous stomatitis"],"prefix":"10.1111","volume":"16","author":[{"given":"S","family":"Piskin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Sayan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Durukan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Senol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,3,14]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"467","article-title":"Recurrent aphthous stomatitis: current etiopathogenetic and therapeutic concepts","volume":"44","author":"Carrozzo M","year":"1995","journal-title":"Minerva Stomatol"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1989.tb00727.x"},{"key":"e_1_2_5_4_2","first-page":"1355","volume-title":"Dermatology in General Medicine","author":"Gallagher BT.","year":"1993"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(96)80437-9"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(88)90064-3"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-2977(98)00096-5"},{"key":"e_1_2_5_8_2","first-page":"85","article-title":"Hematologic deficiencies in patients with recurrent oral aphthae","volume":"109","author":"Barnadas MA","year":"1997","journal-title":"Med Clin"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1468-3083.2002.00369.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1046\/j.1468-3083.2002.00369.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T13:37:48Z","timestamp":1697549868000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1046\/j.1468-3083.2002.00369.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,1]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2002,1]]}},"alternative-id":["10.1046\/j.1468-3083.2002.00369.x"],"URL":"https:\/\/doi.org\/10.1046\/j.1468-3083.2002.00369.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,1]]}}}