{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T04:18:10Z","timestamp":1781756290263,"version":"3.54.5"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2002,3,14]],"date-time":"2002-03-14T00:00:00Z","timestamp":1016064000000},"content-version":"vor","delay-in-days":72,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Rheumatoid neutrophilic dermatitis (RND) is an uncommon, but distinctive manifestation of rheumatoid arthritis (RA). We describe the case of a 35\u2010year\u2010old female who developed RND as an early stage of seronegative RA. Clinically, the lesions were presented by erythematous, slightly tender, papules, 5\u201310\u00a0mm in diameter, on the extensor surface of the left arm. The histopathological findings revealed a dense, dermal, mainly neutrophilic infiltrate, with prominent leucocytoclasia, but without any features of vasculitis. There was fibrinoid degeneration of collagen, resembling the collagen changes present in rheumatoid nodules in a miniaturized form. RND can be a reliable, early clinical sign of RA, as seen in our patient. Furthermore, this case demonstrates that RND may be associated not only with seropositive RA, as described in the literature, but also with seronegative RA, never before reported. The histological findings in our case are remarkable because of the fibrinoid collagen degeneration, which is described here for the first time in RND. Thus, RND may, in fact, be the initial phase of a spectrum that begins with a neutrophilic reaction and mild fibrinoid collagen degeneration, and evolves into rheumatoid nodules at the final stage.<\/jats:p>","DOI":"10.1046\/j.1468-3083.2002.00401.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T04:41:59Z","timestamp":1047444119000},"page":"74-76","source":"Crossref","is-referenced-by-count":17,"title":["Rheumatoid neutrophilic dermatitis: an initial dermatological manifestation of seronegative rheumatoid arthritis"],"prefix":"10.1111","volume":"16","author":[{"given":"A","family":"Lazarov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Mor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Cordoba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YA","family":"Mekori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,3,14]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(83)70049-6"},{"key":"e_1_2_4_3_2","first-page":"3","article-title":"Interstitial granulomatous dermatitis with cutaneous cords in rheumatoid arthritis revisited","volume":"1","author":"Gottlieb GJ","year":"1995","journal-title":"Dermatopathol Pract Conceptual"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199906000-00007"},{"key":"e_1_2_4_5_2","first-page":"449","volume-title":"Histopathologic Diagnosis of Inflammatory Skin Diseases: A Method by Pattern Analysis","author":"Ackerman AB.","year":"1978"},{"key":"e_1_2_4_6_2","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1001\/archderm.1989.01670200081014","article-title":"Rheumatoid neutrophilic dermatitis","volume":"125","author":"Scherbenske JM","year":"1989","journal-title":"Arch Dermatol"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(90)70127-4"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1992.tb01558.x"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1994.tb01000.x"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.131.10.1196"},{"key":"e_1_2_4_11_2","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1001\/archderm.1997.03890420097013","article-title":"Rheumatoid neutrophilic dermatitis","volume":"133","author":"Mashek HA","year":"1997","journal-title":"Arch Dermatol"},{"key":"e_1_2_4_12_2","first-page":"203","article-title":"Rheumatoid neutrophic dermatitis","volume":"60","author":"Hirota TK","year":"1997","journal-title":"Cutis"},{"key":"e_1_2_4_13_2","doi-asserted-by":"crossref","unstructured":"The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis.Arthritis Rheum1988;31:315.","DOI":"10.1002\/art.1780310302"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1468-3083.2002.00401.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1046\/j.1468-3083.2002.00401.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T13:38:35Z","timestamp":1697549915000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1046\/j.1468-3083.2002.00401.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2002,1]]}},"alternative-id":["10.1046\/j.1468-3083.2002.00401.x"],"URL":"https:\/\/doi.org\/10.1046\/j.1468-3083.2002.00401.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,1]]}}}