{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T06:57:47Z","timestamp":1761893867124},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2003,10,24]],"date-time":"2003-10-24T00:00:00Z","timestamp":1066953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2003,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>We present a case of a 78\u2010year\u2010old man suffering from a chronic psoriasiform eruption, with rapid deterioration over the previous 8\u00a0weeks. Langerhans\u2019 cell histiocytosis with skin and bone involvement was diagnosed, and there was evidence of liver and lung dysfunction. The patient was treated with prednisolone and etoposide, and initially experienced a partial improvement. Three weeks later, haemophagocytic lymphohistiocytosis and subsequently a large pulmonary abscess with sepsis attributed to opportunistic gram\u2010negative enterobacteriaceae <jats:italic>Serratia marcescens<\/jats:italic> developed, and the patient died. The present case of Langerhans\u2019 cell histiocytosis is of particular interest because of the previously unreported development of haemophagocytic lymphohistiocytosis in the elderly population.<\/jats:p>","DOI":"10.1046\/j.1468-3083.2003.00840.x","type":"journal-article","created":{"date-parts":[[2003,10,24]],"date-time":"2003-10-24T10:15:18Z","timestamp":1066990518000},"page":"702-705","source":"Crossref","is-referenced-by-count":4,"title":["Langerhans\u2019 cell histiocytosis and haemophagocytic lymphohistiocytosis in an elderly patient"],"prefix":"10.1111","volume":"17","author":[{"given":"D","family":"Ioannidou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Krasagakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Panayiotidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Stefanidou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Alexandrakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Tosca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,10,24]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198703193161211"},{"key":"e_1_2_4_3_2","first-page":"208","article-title":"The writing group of the histiocyte society. 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