{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T01:04:28Z","timestamp":1792717468487,"version":"4.5.0"},"reference-count":41,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2002,7,10]],"date-time":"2002-07-10T00:00:00Z","timestamp":1026259200000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Anatomy"],"published-print":{"date-parts":[[2002,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The formation and transformation of the pharyngeal arch arteries in the mouse embryo, from 8.5 to 13\u00a0days of gestation (DG), was observed using scanning electron microscopy of vascular casts and graphic reconstruction of 1\u2010\u00b5m serial epoxy\u2010resin sections. Late in 8.5\u20139DG (12 somites), the paired ventral aortae were connected to the dorsal aortae via a loop anterior to the foregut which we call the \u2018primitive aortic arch\u2019, as in the chick embryo. The primitive aortic arch extended cranio\u2010caudally to be transformed into the primitive internal carotid artery, which in turn gave rise to the primitive maxillary artery and the arteries supplying the brain. The second pharyngeal arch artery (PAA) appeared late in 9\u20139.5DG (16\u201317 somites), and the ventral aorta bent dorsolaterally to form the first PAA anterior to the first pharyngeal pouch by early in 9.5\u201310DG (21\u201323 somites). The third PAA appeared early in 9.5\u201310DG (21\u201323 somites), the fourth late in 9.5\u201310DG (27\u201329 somites), and the sixth at 10DG (31\u201334 somites). By 10.5DG (35\u201339 somites), the first and second PAAs had been transformed into other arteries, and the third, fourth and sixth PAAs had developed well, though the PAA system still exhibited bilateral symmetry. By 13DG, the right sixth PAA had disappeared, and the remaining PAAs formed an aortic\u2010arch system that was almost of the adult type.<\/jats:p>","DOI":"10.1046\/j.1469-7580.2002.00071.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T07:26:55Z","timestamp":1047454015000},"page":"15-29","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":148,"title":["Development of pharyngeal arch arteries in early mouse embryo"],"prefix":"10.1111","volume":"201","author":[{"given":"Tamiko","family":"Hiruma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Nakajima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,7,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091110207"},{"key":"e_1_2_6_3_1","first-page":"157","article-title":"A volumetric analysis of young human embryos of the 10\u2010 and 12\u2010somite stage","volume":"28","author":"Boyden EA","year":"1940","journal-title":"Contrib. 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