{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T16:05:09Z","timestamp":1764173109050},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2001,12,25]],"date-time":"2001-12-25T00:00:00Z","timestamp":1009238400000},"content-version":"vor","delay-in-days":1395,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[1998,3]]},"abstract":"<jats:sec><jats:title>Background.<\/jats:title><jats:p>Since the bacterium <jats:italic>H. pylori<\/jats:italic> was identified in 1982, overwhelming evidence has implicated it as the causal factor in the occurrence and relapse of peptic ulcer disease. The major objective of this study was to examine the extent to which physicians recognize <jats:italic>H. pylori<\/jats:italic> as a causal agent in peptic ulcer disease or as potential cofactor in other gastrointestinal diseases, and the extent to which this knowledge has influenced diagnostic and therapeutic practices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods.<\/jats:title><jats:p>Using a national mail survey in Germany in September 1995, 1197 family practitioners and 1197 gastroenterologists were selected for the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Of the surveyed physicians, 756 (32%) responded. Family practitioners treated almost 50% of their patients with initial presentation of suspected ulcer disease without ordering further diagnostic tests<jats:italic>.<\/jats:italic> More than 25% of the family practitioners and 14% of the gastroenterologists reported that they do not treat diagnosed <jats:italic>H. pylori<\/jats:italic> infection in the first presentation of duodenal ulcer. At the time we conducted the study, 22% of responding family practitioners and 5% of responding gastroenterologists treated the first presentation of <jats:italic>H. pylori\u2010<\/jats:italic>positive ulcer disease with regimens determined to be ineffective according to the available literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions.<\/jats:title><jats:p>Gastroenterologists preferred to treat <jats:italic>H. pylori<\/jats:italic> infection when the associated disease was one for which a causal relationship had been more clearly established, while family practitioners showed less discrimination. In order to provide optimal therapy aimed at minimizing the course and consequences of <jats:italic>H. pylori<\/jats:italic>\u2010related diseases, researchers in the field must ensure continuous dissemination of current knowledge.<\/jats:p><\/jats:sec>","DOI":"10.1046\/j.1523-5378.1998.08027.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T23:20:28Z","timestamp":1047424828000},"page":"1-8","source":"Crossref","is-referenced-by-count":17,"title":["How Do Practicing Clinicians Manage <i>Helicobacter pylori\u2010<\/i>Related Gastrointestinal Diseases in Germany? A Survey of Gastroenterologists and Family Practitioners"],"prefix":"10.1111","volume":"3","author":[{"given":"Thomas","family":"Breuer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Sudhop","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen J.","family":"Goodman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David Y.","family":"Graham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Malfertheiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,12,25]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"1273","article-title":"Unidentified curved bacilli on gastric epithelium in active chronic gastritis","volume":"1","author":"Marshall BJ","year":"1983","journal-title":"Lancet"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365529109093203"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199110173251603"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199405053301803"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199110173251604"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00051332"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.33.1.16"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-116-9-705"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365529309098288"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)90113-2"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)90645-J"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.302.6788.1302"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198912073212302"},{"key":"e_1_2_6_15_2","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1001\/archinte.1988.00380050153022","article-title":"Gastritis and Campylobacter pylori in healthy, asymptomatic volunteers","volume":"148","author":"Barthel JS","year":"1988","journal-title":"Arch Intern Med"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008469-199502000-00007"},{"key":"e_1_2_6_17_2","first-page":"1","article-title":"Working Group: Schistosomes, liver flukes and Helicobacter pylori. 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