{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:14:56Z","timestamp":1790720096871,"version":"4.1.0"},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2003,5,21]],"date-time":"2003-05-21T00:00:00Z","timestamp":1053475200000},"content-version":"vor","delay-in-days":1966,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Headache"],"published-print":{"date-parts":[[1998,1]]},"abstract":"<jats:p>We examined the lactic and pyruvic acid levels in the plasma of 14 patients with migraine, 17 patients with tension\u2010type headache, and 12 normal controls. The lactic and pyruvic acid levels in the plasma of the migraine patients were significantly higher than those of the normal controls (9.6 \u00b1 5.0 mg\/dL and 0.51 \u00b1 0.30 mg\/dL versus 3.3 \u00b1 1.9 mg\/dL and 0.26 \u00b1 0.20 mg\/dL, respectively). There were no significant differences in the levels between the patients with tension\u2010type headache and normal controls. Our results suggest that migraine patients may have functional abnormalities in mitochondrial energy metabolism.<\/jats:p>","DOI":"10.1046\/j.1526-4610.1998.3801039.x","type":"journal-article","created":{"date-parts":[[2003,5,21]],"date-time":"2003-05-21T11:20:56Z","timestamp":1053516056000},"page":"39-42","source":"Crossref","is-referenced-by-count":54,"title":["Plasma Lactic Acid and Pyruvic Acid Levels in Migraine and Tension\u2010Type Headache"],"prefix":"10.1111","volume":"38","author":[{"given":"Hiroko","family":"Okada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeru","family":"Araga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takao","family":"Takeshima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Nakashima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,5,21]]},"container-title":["Headache: The Journal of Head and Face Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1526-4610.1998.3801039.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/pdf\/10.1046\/j.1526-4610.1998.3801039.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T11:57:47Z","timestamp":1762084667000},"score":1,"resource":{"primary":{"URL":"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/10.1046\/j.1526-4610.1998.3801039.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1998,1]]}},"alternative-id":["10.1046\/j.1526-4610.1998.3801039.x"],"URL":"https:\/\/doi.org\/10.1046\/j.1526-4610.1998.3801039.x","archive":["Portico"],"relation":{},"ISSN":["0017-8748","1526-4610"],"issn-type":[{"value":"0017-8748","type":"print"},{"value":"1526-4610","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,1]]}}}