{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T23:49:03Z","timestamp":1786492143497,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2002,12,14]],"date-time":"2002-12-14T00:00:00Z","timestamp":1039824000000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2002,12]]},"abstract":"<jats:p> <jats:bold>BACKGROUND<\/jats:bold>\n          : Various adverse effects, including cardiac arrest, have been induced by plasma exchange (PE). Electrolyte derangement is frequently observed. The purpose of this study was to assess the effect of PE on the serum ionized magnesium (Mg\n          <jats:sup>2+<\/jats:sup> ) concentration in acute liver failure patients.<\/jats:p><jats:p> <jats:bold>STUDY DESIGN AND METHODS<\/jats:bold>\n          : Seven liver failure patients requiring PE were enrolled in this study. PE was performed 21 times in total. Blood samples were drawn before PE and serially after the start of the PE. Serum Mg\n          <jats:sup>2+<\/jats:sup> was measured by the ion\u2010 selective electrode method.<\/jats:p><jats:p> <jats:bold>RESULTS<\/jats:bold>\n          : After PE was started, Mg\n          <jats:sup>2+<\/jats:sup>\n           concentrations began to fall significantly. The low Mg\n          <jats:sup>2+<\/jats:sup>\n           blood concentration continued during PE. After PE, the Mg\n          <jats:sup>2+<\/jats:sup>\n           level recovered to about 80 percent of the control value within 2 hours in six patients. However, in one patient, the Mg\n          <jats:sup>2+<\/jats:sup> concentration was still low even at 2 hours after PE. This patient complained of chest discomfort during PE and ECG analysis showed sporadic supraventricular premature contractions.<\/jats:p><jats:p> <jats:bold>CONCLUSION<\/jats:bold> : Profound ionized hypomagnesemia was induced by PE in liver failure patients.<\/jats:p>","DOI":"10.1046\/j.1537-2995.2002.00247.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T22:48:56Z","timestamp":1047509336000},"page":"1598-1602","source":"Crossref","is-referenced-by-count":8,"title":["Profound ionized hypomagnesemia induced by therapeutic plasma exchange in liver failure 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