{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T14:10:27Z","timestamp":1783433427240,"version":"3.54.6"},"reference-count":13,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2003,9,5]],"date-time":"2003-09-05T00:00:00Z","timestamp":1062720000000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2003,9]]},"abstract":"<jats:p> <jats:italic>Introduction:<\/jats:italic> Induction of ventricular flutter during electrophysiologic (EP) studies (similar to that of ventricular fibrillation [VF]) often is viewed as a nonspecific response with limited prognostic significance. However, data supporting this dogma originate from patients without previously documented ventricular tachyarrhythmias. We examined the significance of ventricular flutter in patients with and without spontaneous ventricular arrhythmias.<\/jats:p><jats:p> <jats:italic>Methods and Results:<\/jats:italic> We conducted a cohort study of all patients with myocardial infarction (MI) undergoing EP studies at our institution. Of 344 consecutive patients, 181 had previously documented spontaneous sustained ventricular arrhythmias, 61 had <jats:italic>suspected<\/jats:italic> ventricular arrhythmias, and 102 had <jats:italic>neither<\/jats:italic>. Ventricular flutter was induced in 65 (19%) of the patients. Left ventricular ejection fraction was highest among patients with inducible VF (35 \u00b1 13), lowest for patients with inducible sustained monomorphic ventricular tachycardia (SMVT; 27 \u00b1 9), and intermediate for patients with inducible ventricular flutter (30 \u00b1 10). Similarly, the coupling intervals needed to induce the arrhythmia were shortest for VF (200 \u00b1 28 msec), intermediate for ventricular flutter (209 \u00b1 27 msec), and longest for SMVT (230 \u00b1 35 msec). During 5 \u00b1 8 years of follow\u2010up, the risk for ventricular tachycardia\/VF was high for patients with SMVT and ventricular flutter and low for patients with inducible VF and noninducible patients (46%, 34%, 17%, and 14%, P &lt; 0.005).<\/jats:p><jats:p> <jats:italic>Conclusion:<\/jats:italic> Patients with inducible ventricular flutter appear to be \u201cintermediate\u201d between patients with inducible VF and patients with SMVT in terms of clinical and electrophysiologic correlates. However, the prognostic value of inducible ventricular flutter is comparable to that of SMVT. <jats:italic>(J Cardiovasc Electrophysiol, Vol. 14, pp. 913\u2010919, September 2003)<\/jats:italic><\/jats:p>","DOI":"10.1046\/j.1540-8167.2003.03082.x","type":"journal-article","created":{"date-parts":[[2003,9,5]],"date-time":"2003-09-05T09:59:16Z","timestamp":1062755956000},"page":"913-919","source":"Crossref","is-referenced-by-count":14,"title":["Ventricular Flutter Induced During Electrophysiologic Studies in Patients with Old Myocardial Infarction:"],"prefix":"10.1111","volume":"14","author":[{"given":"SAMI","family":"VISKIN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MAYA","family":"ISH\u2010SHALOM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EDWARD","family":"KOIFMAN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"URI","family":"ROZOVSKI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DAVID","family":"ZELTSER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AHARON","family":"GLICK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ARIEL","family":"FINKELSTEIN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AMIR","family":"HALKIN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ROMAN","family":"FISH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BERNARD","family":"BELHASSEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,9,5]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)80576-1"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2003.03082.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(91)90802-G"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199612263352601"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199912163412503"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.69.1.20"},{"key":"e_1_2_5_8_2","first-page":"425","volume-title":"Clinical Cardiac Electrophysiology: Techniques and Interpretations","author":"Josephson ME","year":"2002"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.74.4.731"},{"key":"e_1_2_5_10_2","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1161\/01.CIR.83.3.756","article-title":"What is the best predictor of spontaneous ventricular tachycardia and sudden death after myocardial infarction?","volume":"83","author":"Richards D","year":"1991","journal-title":"Circulation"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1997.tb06100.x"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1991.tb04136.x"},{"key":"e_1_2_5_13_2","first-page":"612","article-title":"Inducible ventricular flutter: not an innocent finding","volume":"24","author":"Gurevitz O","year":"2002","journal-title":"Pacing Clin Electrophysiol"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2002.01103.x"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1540-8167.2003.03082.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1046\/j.1540-8167.2003.03082.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T10:53:40Z","timestamp":1694429620000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1046\/j.1540-8167.2003.03082.x"}},"subtitle":["Clinical and Electrophysiologic Predictors, and Prognostic Significance"],"short-title":[],"issued":{"date-parts":[[2003,9]]},"references-count":13,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2003,9]]}},"alternative-id":["10.1046\/j.1540-8167.2003.03082.x"],"URL":"https:\/\/doi.org\/10.1046\/j.1540-8167.2003.03082.x","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,9]]}}}