{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T15:46:45Z","timestamp":1771516005219,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2004,11,29]],"date-time":"2004-11-29T00:00:00Z","timestamp":1101686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2004,12]]},"abstract":"<jats:p> <jats:italic>Introduction:<\/jats:italic> Entrainment mapping is a useful procedure for localizing macroreentrant tachycardia circuits. In patients with isthmus\u2010dependent atrial flutter, entrainment mapping from the isthmus during tachycardia results in postpacing intervals (PPI) close to the tachycardia cycle length (TCL). However, the influence of antiarrhythmic drugs on the method's value is not clearly established. The aim of our study was to assess the value of entrainment mapping in the presence of amiodarone in patients undergoing radiofrequency ablation (RFA) of isthmus\u2010dependent atrial flutter.<\/jats:p><jats:p> <jats:italic>Methods and Results:<\/jats:italic> The study consisted of 83 patients with isthmus\u2010dependent atrial flutter: 52 were taking amiodarone at the time of RFA (group 1) and 31 were in a drug\u2010free state (group 2). Entrainment mapping was performed from the cavotricuspid isthmus, and PPI minus TCL was determined. The two groups had similar baseline clinical characteristics. In all patients, RFA of the isthmus resulted in termination of tachycardia, confirming the isthmus\u2010dependent nature of the flutter. TCL was significantly longer in group 1 than in group 2 (263 \u00b1 31 msec vs 238 \u00b1 27 msec, P &lt; 0.0002). PPI minus TCL at the isthmus was significantly longer in group 1 than in group 2 (17 \u00b1 17 msec vs 8 \u00b1 4 msec, P &lt; 0.01). More patients in group 1 had PPI\u2010TCL&gt;20 msec compared to group 2 (37% vs 10%, P = 0.01).<\/jats:p><jats:p> <jats:italic>Conclusion:<\/jats:italic> Amiodarone significantly alters the entrainment mapping response from the isthmus. In this setting, long return cycles exceeding the TCL by &gt;20 msec do not exclude isthmus\u2010dependent atrial flutter.<\/jats:p>","DOI":"10.1046\/j.1540-8167.2004.04278.x","type":"journal-article","created":{"date-parts":[[2004,12,13]],"date-time":"2004-12-13T22:54:30Z","timestamp":1102978470000},"page":"1409-1415","source":"Crossref","is-referenced-by-count":12,"title":["Value of Entrainment Mapping in Determining the Isthmus\u2010Dependent Nature of Atrial Flutter in the Presence of Amiodarone"],"prefix":"10.1111","volume":"15","author":[{"given":"MARJANEH","family":"FATEMI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JACQUES","family":"MANSOURATI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RADU","family":"ROSU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JEAN\u2010JACQUES","family":"BLANC","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,12,13]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.6.1389"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(96)00345-2"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.2.284"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.3.270"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1997.tb00775.x"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.25.2928"},{"key":"e_1_2_6_8_2","first-page":"233","volume-title":"Radiofrequency Catheter Ablation of Cardiac Arrhythmias","author":"Kall JG","year":"2000"},{"key":"e_1_2_6_9_2","first-page":"241","volume-title":"Atrial Flutter","author":"Waldo AL","year":"1996"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.89.5.2117"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.7.1839"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.2001.2658"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.3.407"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1067\/mcp.2000.107047"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.83.5.1716"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1987.tb05974.x"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.90.6.2804"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.80.4.793"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.88.4.1647"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1999.1865"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1999.tb00293.x"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(98)00992-8"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.11.1441"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1540-8167.2004.04278.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1046\/j.1540-8167.2004.04278.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1046\/j.1540-8167.2004.04278.x","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1046\/j.1540-8167.2004.04278.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T03:59:20Z","timestamp":1694404760000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1046\/j.1540-8167.2004.04278.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12]]},"references-count":22,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2004,12]]}},"alternative-id":["10.1046\/j.1540-8167.2004.04278.x"],"URL":"https:\/\/doi.org\/10.1046\/j.1540-8167.2004.04278.x","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,12]]}}}