{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:53:16Z","timestamp":1780732396333,"version":"3.54.1"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2003,12,15]],"date-time":"2003-12-15T00:00:00Z","timestamp":1071446400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Ophthalmologica Scandinavica"],"published-print":{"date-parts":[[2004,2]]},"abstract":"<jats:title>Abstract.<\/jats:title><jats:p><jats:bold>Purpose:\u2002<\/jats:bold>An updated analysis of the trends in a Danish county regarding retinopathy of prematurity (ROP), outlining its natural history over the years 1982\u20132001.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold>Epidemiological data are given of the 132 infants in the county with birth years 1998\u20132001 prospectively under surveillance for ROP. The customary national screening limits of gestational age (GA) and birthweight (BW) of 32\u2003weeks\/1750\u2003g were generally adhered to. The findings are compared to five previous consecutive reports of a similar set\u2010up, now making a total of 1123 who have been under surveillance.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold>With focus on the 20\u2003years' newborns at a higher risk for ROP in the county (GA\/BW both under the above limits;<jats:italic>n<\/jats:italic>\u2003=\u2003591) the continuous improvement up to 1998\u2003\u2212\u2003as reflected by ROP frequency, its severity, and risk levels according to GA\/BW\u2003\u2212\u2003appears to have been interrupted. Compared to the previous 4\u2010year period, the percentage acquiring ROP in 1998\u20132001 increased from 10 to 31%, and four recent cases qualified for retinal ablation therapy, compared with zero in the previous 4\u2010year period. However, there were no advanced stages (of at least ROP\u20033) in infants above 30\u2003weeks\/1500 g at delivery.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold>(a) Using the ROP also as a neonatal treatment quality parameter, the present trend (progress stopped) should be followed attentively. So far, we have no clues regarding therapy\u2010related or other causality. (b) Despite the suggested worsening, a lowering of the ophthalmic GA and BW screening limits now seems justifiable. With a view also to the high\u2010risk Copenhagen data and the national childhood visual impairment register, a reduction of the values to 31\u2003weeks\/1500\u2003g should be considered.<\/jats:p>","DOI":"10.1046\/j.1600-0420.2003.00199.x","type":"journal-article","created":{"date-parts":[[2004,12,19]],"date-time":"2004-12-19T12:31:54Z","timestamp":1103459514000},"page":"38-41","source":"Crossref","is-referenced-by-count":20,"title":["Surveillance for retinopathy of prematurity in a Danish county. Epidemiological experience over 20\u2003years"],"prefix":"10.1111","volume":"82","author":[{"given":"Hans C.","family":"Fledelius","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit","family":"Kjer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,12,15]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1988.01060130517027"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1990.tb01906.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1755-3768.1993.tb04155.x","article-title":"Retinopathy of prematurity in Frederiksborg County 1988\u201390. A prospective investigation, an update","volume":"210","author":"Fledelius HC","year":"1993","journal-title":"Acta Ophthalmol Scand Suppl"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/112067219600600216"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.1996.tb00096.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.2000.078003359.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1600-0420.2003.00198.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1990.tb11351.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1997.136"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.77.7.417"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.68.10.690"},{"key":"e_1_2_5_13_1","first-page":"3","volume-title":"Progress in Retinopathy of Prematurity.","author":"Koerner F","year":"1997"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.120.11.1470"},{"key":"e_1_2_5_15_1","unstructured":"The Royal College of Ophthalmologists. British Association of Perinatal Medicine(1995):Retinopathy of prematurity. Guidelines for Screening and Treatment."}],"container-title":["Acta Ophthalmologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1600-0420.2003.00199.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1046\/j.1600-0420.2003.00199.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T02:30:49Z","timestamp":1705458649000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1046\/j.1600-0420.2003.00199.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,12,15]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,2]]}},"alternative-id":["10.1046\/j.1600-0420.2003.00199.x"],"URL":"https:\/\/doi.org\/10.1046\/j.1600-0420.2003.00199.x","archive":["Portico"],"relation":{},"ISSN":["1395-3907","1600-0420"],"issn-type":[{"value":"1395-3907","type":"print"},{"value":"1600-0420","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,12,15]]}}}