{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:26:17Z","timestamp":1761560777729},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2002,7,1]],"date-time":"2002-07-01T00:00:00Z","timestamp":1025481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"},{"start":{"date-parts":[[2002,6,25]],"date-time":"2002-06-25T00:00:00Z","timestamp":1024963200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2002,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The evolution of fitness is central to evolutionary theory, yet few experimental systems allow us to track its evolution in genetically and environmentally relevant contexts. Reverse evolution experiments allow the study of the evolutionary return to ancestral phenotypic states, including fitness. This in turn permits well-defined tests for the dependence of adaptation on evolutionary history and environmental conditions. In the experiments described here, 20 populations of heterogeneous evolutionary histories were returned to their common ancestral environment for 50 generations, and were then compared with both their immediate differentiated ancestors and populations which had remained in the ancestral environment. One measure of fitness returned to ancestral levels to a greater extent than other characters did. The phenotypic effects of reverse evolution were also contingent on previous selective history. Moreover, convergence to the ancestral state was highly sensitive to environmental conditions. The phenotypic plasticity of fecundity, a character directly selected for, evolved during the experimental time frame. Reverse evolution appears to force multiple, diverged populations to converge on a common fitness state through different life-history and genetic changes.<\/jats:p>","DOI":"10.1046\/j.1420-9101.2002.00424.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T04:50:09Z","timestamp":1047444609000},"page":"608-617","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Reverse evolution of fitness in <i>Drosophila melanogaster<\/i>"],"prefix":"10.1093","volume":"15","author":[{"given":"H.","family":"Teot\u00f3nio","sequence":"first","affiliation":[{"name":"Department of Ecology and Evolutionary Biology, University of California Irvine, Irvine, CA, USA &#x2028;"}]},{"given":"M.","family":"Matos","sequence":"additional","affiliation":[{"name":"Centro de Biologia Ambiental, Department Zoologiae Antropologia, Faculdade de Ci\u00eancias da Universidade de Lisboa, Campo Grande, Portugal"}]},{"given":"M. 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