{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T15:11:19Z","timestamp":1773155479438,"version":"3.50.1"},"reference-count":11,"publisher":"Institution of Engineering and Technology (IET)","issue":"3","license":[{"start":{"date-parts":[[2016,7,5]],"date-time":"2016-07-05T00:00:00Z","timestamp":1467676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Healthcare Tech Letters"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:p>\n                    Hydrocephalus is a condition characterised by enlarged cerebral ventricles, which in turn affects intracranial pressure (ICP); however, the mechanisms regulating ICP are not fully understood. A nonlinear signal processing approach was applied to ICP signals measured during infusion studies from patients with two forms of hydrocephalus, in a bid to compare the differences. This is the first study of its kind. The two forms of hydrocephalus were idiopathic normal pressure hydrocephalus (iNPH) and secondary normal pressure hydrocephalus (SH). Following infusion tests, the Lempel\u2013Ziv (LZ) complexity was calculated from the iNPH and SH ICP signals. The LZ complexity values were averaged for the baseline, infusion, plateau and recovery stages of the tests. It was found that as the ICP increased from basal levels, the LZ complexities decreased, reaching their lowest during the plateau stage. However, the complexities computed from the SH ICP signals decreased to a lesser extent when compared with the iNPH ICP signals. Furthermore, statistically significant differences were found between the plateau and recovery stage complexities when comparing the iNPH and SH results (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.05). This Letter suggests that advanced signal processing of ICP signals with LZ complexity can help characterise different types of hydrocephalus in more detail.\n                  <\/jats:p>","DOI":"10.1049\/htl.2016.0018","type":"journal-article","created":{"date-parts":[[2016,6,14]],"date-time":"2016-06-14T14:20:06Z","timestamp":1465914006000},"page":"226-229","source":"Crossref","is-referenced-by-count":1,"title":["Characterisation of the complexity of intracranial pressure signals measured from idiopathic and secondary normal pressure hydrocephalus patients"],"prefix":"10.1049","volume":"3","author":[{"given":"Tricia","family":"Adjei","sequence":"first","affiliation":[{"name":"Centre for Biomedical Engineering, Department of Mechanical Engineering Sciences, Faculty of Engineering and Physical Sciences University of Surrey  Guildford UK"},{"name":"Department of Electrical and Electronic Engineering Imperial College London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Ab\u00e1solo","sequence":"additional","affiliation":[{"name":"Centre for Biomedical Engineering, Department of Mechanical Engineering Sciences, Faculty of Engineering and Physical Sciences University of Surrey  Guildford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Santamarta","sequence":"additional","affiliation":[{"name":"Servicio de Neurocirug\u00eda Hospital Universitario  Le\u00f3n Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"265","published-online":{"date-parts":[[2016,7,5]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"An introduction to neurosurgery","author":"Jennett B.","year":"1983"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00381\u2010010\u20101244\u20105"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medengphy.2013.04.002"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aws155"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.20.6.534"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1109\/TIT.1976.1055501"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1109\/10.759055"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4612-0921-8"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000190426.44782.F0"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0197\u20104580(01)00266\u20104"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1995.83.6.0949"}],"container-title":["Healthcare Technology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1049\/htl.2016.0018","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1049\/htl.2016.0018","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ietresearch.onlinelibrary.wiley.com\/doi\/pdf\/10.1049\/htl.2016.0018","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T11:51:43Z","timestamp":1761565903000},"score":1,"resource":{"primary":{"URL":"https:\/\/ietresearch.onlinelibrary.wiley.com\/doi\/10.1049\/htl.2016.0018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,5]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1049\/htl.2016.0018"],"URL":"https:\/\/doi.org\/10.1049\/htl.2016.0018","archive":["Portico"],"relation":{},"ISSN":["2053-3713","2053-3713"],"issn-type":[{"value":"2053-3713","type":"print"},{"value":"2053-3713","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,5]]}}}